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Micromachines
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Biomaterials, Biodevices and Tissue Engineering, Second Edition
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Biomaterials, Biodevices and Tissue Engineering, Second Edition

A special issue of Micromachines (ISSN 2072-666X). This special issue belongs to the section "B2: Biofabrication and Tissue Engineering".

Deadline for manuscript submissions: 30 December 2024 | Viewed by 3393

Special Issue Editors

Dr. Luis Jesús Villarreal-Gómez

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Guest Editor
Facultad de Ciencias de la Ingeniería y Tecnología, Universidad Autónoma de Baja California, Tijuana 21500, Baja California, Mexico
Interests: tissue engineering; drug delivery systems; biotechnology; nanotechnology; electrospinning; biosensors
Special Issues, Collections and Topics in MDPI journals
Dr. Jose Manuel Cornejo-Bravo

E-Mail Website
Guest Editor
Facultad de Ciencias Químicas e Ingeniería, Universidad Autónoma de Baja California, Calzada Universidad 14418, Parque Industrial Internacional, Tijuana 22300, Mexico
Interests: pharmacology; nanomedicine; pharmacy; clinical pharmacology; pharmacovigilance
Special Issues, Collections and Topics in MDPI journals
Dr. Faruk Fonthal Rico

E-Mail Website
Guest Editor
Biomedical Engineering Research Group—GBIO, Universidad Autónoma de Occidente, Cali 760030, Colombia
Interests: optoelectronics; biomaterials; bioengineering; drug delivery systems
Special Issues, Collections and Topics in MDPI journals

Special Issue Information

Dear Colleagues,

The innovation in biomaterials in several forms, compositions, and uses has seen exponential growth over the past 10 years and has led to increased confidence in the industry as regards the design and fabrication of biomedical devices that can be used as drug delivery systems, in tissue engineering, and as bioelectronic devices such as biosensors or organic solar cells. The choice and adequation of the optimal biomaterial for a specific application with a cost-effective manufacturing process have been the objective of even more scientists around the world. Additionally, the construction of nanostructures has led to many advantageous characteristics of these biomaterials, stimulating their bioactivity due to the accessibility of many tissues or incrementing the surface area, leading to a higher load of a bioactive component, among others. One example is the use of the electrospinning technique, which permits the fabrication of tridimensional fibrous structures that simulate the tissue’s extracellular matrix, which promotes cell proliferation. Accordingly, this Special Issue seeks to showcase research papers, communications, and review articles that focus on novel methodological developments in micro- and nano-scale fabrication, novel synthesis processes, chemical compositions, nanostructures, coatings, or bioactivity and tissue response in areas of application of tissue engineering, drug delivery systems, and biomedical devices.

We look forward to receiving your submissions.

Dr. Luis Jesús Villarreal-Gómez
Dr. Jose Manuel Cornejo-Bravo
Dr. Faruk Fonthal Rico
Guest Editors

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Micromachines is an international peer-reviewed open access monthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2600 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • biomaterials
  • biodevices
  • tissue engineering
  • drug delivery systems
  • biosensors
  • nanotechnology

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Related Special Issue

Published Papers (2 papers)

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Research

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19 pages, 6389 KiB  
Article
A Breast Tumor Monitoring Vest with Flexible UWB Antennas—A Proof-of-Concept Study Using Realistic Breast Phantoms
by Rakshita Dessai, Daljeet Singh, Marko Sonkki, Jarmo Reponen, Teemu Myllylä, Sami Myllymäki and Mariella Särestöniemi
Micromachines 2024, 15(9), 1153; https://doi.org/10.3390/mi15091153 - 14 Sep 2024
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Abstract
Breast cancers can appear and progress rapidly, necessitating more frequent monitoring outside of hospital settings to significantly reduce mortality rates. Recently, there has been considerable interest in developing techniques for portable, user-friendly, and low-cost breast tumor monitoring applications, enabling frequent and cost-efficient examinations. [...] Read more.
Breast cancers can appear and progress rapidly, necessitating more frequent monitoring outside of hospital settings to significantly reduce mortality rates. Recently, there has been considerable interest in developing techniques for portable, user-friendly, and low-cost breast tumor monitoring applications, enabling frequent and cost-efficient examinations. Microwave technique-based breast cancer detection, which is based on differential dielectric properties of malignant and healthy tissues, is regarded as a promising solution for cost-effective breast tumor monitoring. This paper presents the development process of the first proof-of-concept of a breast tumor monitoring vest which is based on the microwave technique. Two unique vests are designed and evaluated on realistic 3D human tissue phantoms having different breast density types. Additionally, the measured results are verified using simulations carried out on anatomically realistic voxel models of the electromagnetic simulations. The radio channel characteristics are evaluated and analyzed between the antennas embedded in the vest in tumor cases and reference cases. Both measurements and simulation results show that the proposed vest can detect tumors even if only 1 cm in diameter. Additionally, simulation results show detectability with 0.5 cm tumors. It is observed that the detectability of breast tumors depends on the frequency, antenna selection, size of the tumors, and breast types, causing differences of 0.5–30 dB in channel responses between the tumorous and reference cases. Due to simplicity and cost-efficiency, the proposed channel analysis-based breast monitoring vests can be used for breast health checks in smaller healthcare centers and for user-friendly home monitoring which can prove beneficial in rural areas and developing countries. Full article
(This article belongs to the Special Issue Biomaterials, Biodevices and Tissue Engineering, Second Edition)
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Review

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21 pages, 2154 KiB  
Review
Biomaterials for Protein Delivery: Opportunities and Challenges to Clinical Translation
by Amogh Gorantla, Jacques T. V. E. Hall, Anneliese Troidle and Jelena M. Janjic
Micromachines 2024, 15(4), 533; https://doi.org/10.3390/mi15040533 - 15 Apr 2024
Viewed by 1965
Abstract
The development of biomaterials for protein delivery is an emerging field that spans materials science, bioengineering, and medicine. In this review, we highlight the immense potential of protein-delivering biomaterials as therapeutic options and discuss the multifaceted challenges inherent to the field. We address [...] Read more.
The development of biomaterials for protein delivery is an emerging field that spans materials science, bioengineering, and medicine. In this review, we highlight the immense potential of protein-delivering biomaterials as therapeutic options and discuss the multifaceted challenges inherent to the field. We address current advancements and approaches in protein delivery that leverage stimuli-responsive materials, harness advanced fabrication techniques like 3D printing, and integrate nanotechnologies for greater targeting and improved stability, efficacy, and tolerability profiles. We also discuss the demand for highly complex delivery systems to maintain structural integrity and functionality of the protein payload. Finally, we discuss barriers to clinical translation, such as biocompatibility, immunogenicity, achieving reliable controlled release, efficient and targeted delivery, stability issues, scalability of production, and navigating the regulatory landscape for such materials. Overall, this review summarizes insights from a survey of the current literature and sheds light on the interplay between innovation and the practical implementation of biomaterials for protein delivery. Full article
(This article belongs to the Special Issue Biomaterials, Biodevices and Tissue Engineering, Second Edition)
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