Photonic Crystal Microsensors

A special issue of Micromachines (ISSN 2072-666X). This special issue belongs to the section "A:Physics".

Deadline for manuscript submissions: closed (30 June 2020) | Viewed by 8884

Special Issue Editor


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Guest Editor
Valencia Nanophotonics Technology Center, Universitat Politecnica de Valencia, Valencia, Spain
Interests: photonic biosensors; photonic crystals; lab-on-a-chip; porous silicon

Special Issue Information

Dear Colleagues,

Since their proposal in the late 80s, photonic crystals have become one of the hottest topics in the field of nanophotonics due to their ability to control light at the nanoscale. By properly tuning the parameters of these structures, it is possible to achieve the presence of photonic bandgaps, obtain slow-wave propagation, or control the dispersion properties of the propagated modes. Although the main application of photonic crystals was related to the signal processing and light control fields, they have also demonstrated outstanding performances for sensing-related applications. Their special properties can achieve very high sensitivities while keeping a very reduced footprint, which is a must for the development of, for example, lab-on-a-chip devices. This Special Issue seeks reviews, regular research papers, and short communications on the different aspects related with the development of photonic crystal-based microsensors, from the proposal of novel configurations of these sensing structures to the experimental demonstration of their application in different fields.

Prof. Jaime García-Rupérez
Guest Editor

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Keywords

  • Photonic crystals
  • Biosensors
  • Mechanical sensors
  • Optomechanics
  • Lab-on-a-Chip
  • Sensor design and optimization
  • Photonic crystals fabrication and testing

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Published Papers (2 papers)

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Research

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12 pages, 2399 KiB  
Article
Continuous Detection of Increasing Concentrations of Thrombin Employing a Label-Free Photonic Crystal Aptasensor
by Paula Martínez-Pérez, Maribel Gómez-Gómez, Todora Angelova, Amadeu Griol, Juan Hurtado, Laurent Bellieres and Jaime García-Rupérez
Micromachines 2020, 11(5), 464; https://doi.org/10.3390/mi11050464 - 28 Apr 2020
Cited by 9 | Viewed by 2287
Abstract
Thrombin generation is a complex and finely regulated pathway that provokes dynamical changes of thrombin concentration in blood when a vascular injury occurs. In order to characterize the initiation phase of such process, when thrombin concentration is in the nM range, a label-free [...] Read more.
Thrombin generation is a complex and finely regulated pathway that provokes dynamical changes of thrombin concentration in blood when a vascular injury occurs. In order to characterize the initiation phase of such process, when thrombin concentration is in the nM range, a label-free optical aptasensor is proposed here. This aptasensor combines a 1D photonic crystal structure consisting of a silicon corrugated waveguide with thrombin binding aptamers on its surface as bioreceptors. As a result, this aptasensor has been demonstrated to specifically detect thrombin concentrations ranging from 270 pM to 27 nM with an estimated detection limit of 33.5 pM and a response time of ~2 min. Furthermore, it has also been demonstrated that this aptasensor is able to continuously respond to consecutive increasing concentrations of thrombin and to detect binding events as they occur. All these features make this aptasensor a good candidate to continuously study how thrombin concentration progressively increases during the initiation phase of the coagulation cascade. Full article
(This article belongs to the Special Issue Photonic Crystal Microsensors)
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Review

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20 pages, 11418 KiB  
Review
Photonic Crystal Nanobeam Cavities for Nanoscale Optical Sensing: A Review
by Da-Quan Yang, Bing Duan, Xiao Liu, Ai-Qiang Wang, Xiao-Gang Li and Yue-Feng Ji
Micromachines 2020, 11(1), 72; https://doi.org/10.3390/mi11010072 - 9 Jan 2020
Cited by 45 | Viewed by 6088
Abstract
The ability to detect nanoscale objects is particular crucial for a wide range of applications, such as environmental protection, early-stage disease diagnosis and drug discovery. Photonic crystal nanobeam cavity (PCNC) sensors have attracted great attention due to high-quality factors and small-mode volumes (Q/V) [...] Read more.
The ability to detect nanoscale objects is particular crucial for a wide range of applications, such as environmental protection, early-stage disease diagnosis and drug discovery. Photonic crystal nanobeam cavity (PCNC) sensors have attracted great attention due to high-quality factors and small-mode volumes (Q/V) and good on-chip integrability with optical waveguides/circuits. In this review, we focus on nanoscale optical sensing based on PCNC sensors, including ultrahigh figure of merit (FOM) sensing, single nanoparticle trapping, label-free molecule detection and an integrated sensor array for multiplexed sensing. We believe that the PCNC sensors featuring ultracompact footprint, high monolithic integration capability, fast response and ultrahigh sensitivity sensing ability, etc., will provide a promising platform for further developing lab-on-a-chip devices for biosensing and other functionalities. Full article
(This article belongs to the Special Issue Photonic Crystal Microsensors)
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