Novel Approaches in the Diagnosis and Control of Emerging Pathogens

A special issue of Microorganisms (ISSN 2076-2607). This special issue belongs to the section "Medical Microbiology".

Deadline for manuscript submissions: 30 November 2024 | Viewed by 757

Special Issue Editors


E-Mail Website
Guest Editor
Microbiology and Virology Laboratory, A.O.U. “SS Antonio e Biagio e C. Arrigo”, Via Venezia 16, 15121 Alessandria, Italy
Interests: clinical microbiology; virology; molecular biology; next generation sequencing

E-Mail Website
Guest Editor
Microbiology and Virology Laboratory, A.O.U. “SS Antonio e Biagio e C. Arrigo”, Via Venezia 16, 15121 Alessandria, Italy
Interests: clinical microbiology; antimicrobial resistance; POCT; next generation sequencing

Special Issue Information

Dear Colleagues,

In the face of evolving microbial threats, advancements in sequencing technologies (i.e., next-generation sequencing), molecular biology, point-of-care testing (POCT) and so-called lab-on-chip have revolutionized our ability to swiftly diagnose emerging pathogens with unprecedented accuracy and speed. This Special Issue delves into the application of these novel approaches, showcasing their efficacy in the rapid identification and characterization of infectious agents, thereby enhancing early intervention strategies.

Moreover, in alignment with the new One Health paradigm, this Special Issue will emphasize the importance of holistic approaches to monitoring and controlling emerging pathogens.

Authors are encouraged to submit original research articles, communications and reviews that explore cutting-edge methodologies transforming the landscape of emerging pathogen detection and management, with a focus on strategies and approaches that allow us to understand the interactions among human, animal and environmental health domains. Contributions from all fields of microbiology, spanning human health, veterinary medicine, clinical research and beyond are welcomed.

We encourage colleagues worldwide to participate in this collaborative endeavor in order to push the boundaries of microbial surveillance and management, thus fostering a comprehensive understanding of novel pathogen dynamics and transmission pathways through innovative diagnostic and control strategies.

Dr. Paolo Bottino
Dr. Andrea Rocchetti
Guest Editors

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Microorganisms is an international peer-reviewed open access monthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2700 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • one Health approach
  • sequencing
  • point of care testing
  • emerging pathogens
  • rapid diagnosis
  • surveillance strategies

Benefits of Publishing in a Special Issue

  • Ease of navigation: Grouping papers by topic helps scholars navigate broad scope journals more efficiently.
  • Greater discoverability: Special Issues support the reach and impact of scientific research. Articles in Special Issues are more discoverable and cited more frequently.
  • Expansion of research network: Special Issues facilitate connections among authors, fostering scientific collaborations.
  • External promotion: Articles in Special Issues are often promoted through the journal's social media, increasing their visibility.
  • e-Book format: Special Issues with more than 10 articles can be published as dedicated e-books, ensuring wide and rapid dissemination.

Further information on MDPI's Special Issue polices can be found here.

Published Papers (1 paper)

Order results
Result details
Select all
Export citation of selected articles as:

Research

9 pages, 893 KiB  
Article
“CLADE-FINDER”: Candida auris Lineage Analysis Determination by Fourier Transform Infrared Spectroscopy and Artificial Neural Networks
by Carlotta Magrì, Elena De Carolis, Vittorio Ivagnes, Vincenzo Di Pilato, Bram Spruijtenburg, Anna Marchese, Eelco F. J. Meijer, Anuradha Chowdhary and Maurizio Sanguinetti
Microorganisms 2024, 12(11), 2153; https://doi.org/10.3390/microorganisms12112153 - 26 Oct 2024
Viewed by 589
Abstract
In 2019, Candida auris became the first fungal pathogen included in the list of the urgent antimicrobial threats by the Centers for Disease Control (CDC). Short tandem repeat (STR) analysis and whole-genome sequencing (WGS) are considered the gold standard, and can be complemented [...] Read more.
In 2019, Candida auris became the first fungal pathogen included in the list of the urgent antimicrobial threats by the Centers for Disease Control (CDC). Short tandem repeat (STR) analysis and whole-genome sequencing (WGS) are considered the gold standard, and can be complemented by other molecular methods, for the genomic surveillance and clade classification of this multidrug-resistant yeast. However, these methods can be expensive and require time and expertise that are not always available. The long turnaround time is especially not compatible with the speed needed to manage clonal transmission in healthcare settings. Fourier transform infrared (FTIR) spectroscopy, a biochemical fingerprint approach, has been applied in this study to a set of 74 C. auris isolates belonging to the five clades of C. auris (I-V) in combination with an artificial neural network (ANN) algorithm to create and validate “CLADE-FINDER”, a tool for C. auris clade determination. The CLADE-FINDER classifier allowed us to discriminate the four primary C. auris clades (I-IV) with a correct classification for 96% of the samples in the validation set. This newly developed genotyping scheme can be reasonably applied for the effective epidemiological monitoring and management of C. auris cases in real time. Full article
(This article belongs to the Special Issue Novel Approaches in the Diagnosis and Control of Emerging Pathogens)
Show Figures

Figure 1

Back to TopTop