Effects of Respiratory Viral Infections on the Nervous System
A special issue of Microorganisms (ISSN 2076-2607). This special issue belongs to the section "Medical Microbiology".
Deadline for manuscript submissions: 15 March 2025 | Viewed by 5900
Special Issue Editors
Interests: polyomaviruses; neurotropic viruses; viruses and tumors; viruses and central nervous diseases; human endogenous eetroviruses; viruses in immunosuppressed hosts
Special Issues, Collections and Topics in MDPI journals
Interests: neuroimmunology; respiratory viral infection; cognition and behavior impairment; neurotrophins and neurotransmitters
Special Issues, Collections and Topics in MDPI journals
Special Issue Information
Dear Colleagues,
Central nervous system (CNS) infections are one of the most important public health problems because, commonly, patients remain with neurologic sequelae. Usually, CNS pathologies are caused by known neurotropic viruses such as measles and human immunodeficiency virus, among others. However, today respiratory viruses have positioned themselves as relevant causal agents of CNS pathologies. These viral agents are the leading cause of acute respiratory infections yearly, mainly affecting children and the elderly. Several reports exist describing the association of respiratory viral infections with neurological complications. The most frequent symptoms described in these patients are febrile or afebrile seizures, status epilepticus, encephalopathies, and encephalitis. Some of these viruses have been found in the cerebrospinal fluid (CSF) of patients infected with these viruses, which suggests that all these pathogens may be able to spread from the lungs and reach the CNS. However, other respiratory viruses have effects on the CNS without reaching it. After resolving the viral infection, the local immune response can remain active in both cases, contributing to long-term neuropsychiatric disorders, neurocognitive impairment, and degenerative diseases. By understanding the effects of respiratory viral infections of CNS, it is possible to develop new strategies to prevent or treat them. In this Special Issue of Microorganisms, we invite researchers to contribute original research and review articles dealing with respiratory infection of CNS, their pathological mechanisms involved in the long-term sequelae, host CNS immune responses, and therapeutic strategies to reduce patient morbidity and mortality.
Prof. Dr. Pasquale Ferrante
Dr. Karen Bohmwald
Guest Editors
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