Search for Articles:
Title / Keyword
Author / Affiliation / Email
Journal
Article Type
 
 
Advanced Search
 
Section
Special Issue
Volume
Issue
Number
Page
 
7.4
4.1
Journals
Microorganisms
Special Issues
Nontuberculous Mycobacteria: Emerging Diseases and Health Impacts 2.0
share announcement

Nontuberculous Mycobacteria: Emerging Diseases and Health Impacts 2.0

A special issue of Microorganisms (ISSN 2076-2607). This special issue belongs to the section "Medical Microbiology".

Deadline for manuscript submissions: closed (31 October 2023) | Viewed by 8218

Special Issue Editor

Prof. Dr. Roger Pickup

E-Mail Website
Guest Editor
Division of Biomedical and Life Sciences, Faculty of Health and Medicine, Lancaster University, B078 Furness Building, Lancaster LA1 4YQ, UK
Interests: crohn’s disease; paratuberculosis; pathogens; environment
Special Issues, Collections and Topics in MDPI journals

Special Issue Information

Dear Colleagues,

This Special Issue is the continuation of our previous Special Issue "Non-Tuberculous Mycobacteria: Emerging Diseases and Health Impacts".

Non-tuberculous mycobacteria (NTM) are ubiquitous in the environment and have been identified repeatedly from the soil, as well as municipal and other water supplies, by using both molecular and traditional methods. NTM are important environmental pathogens that can cause a broad spectrum of diseases. The number of infections that can be associated with specific species, as well as the number of new species that are etiological agents, has increased due to the development of new diagnostic tools. The incidence of pulmonary NTM infection and disease, as well as the prevalence of Buruli ulcer (Mycobacterium ulcerans), is increasing. In addition, the M. avium complex is implicated in a wide number of diseases. This Special Issue will explore the environmental distribution, detection, and health impact of NTM.

Prof. Dr. Roger Pickup
Guest Editor

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Microorganisms is an international peer-reviewed open access monthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2700 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Benefits of Publishing in a Special Issue

  • Ease of navigation: Grouping papers by topic helps scholars navigate broad scope journals more efficiently.
  • Greater discoverability: Special Issues support the reach and impact of scientific research. Articles in Special Issues are more discoverable and cited more frequently.
  • Expansion of research network: Special Issues facilitate connections among authors, fostering scientific collaborations.
  • External promotion: Articles in Special Issues are often promoted through the journal's social media, increasing their visibility.
  • e-Book format: Special Issues with more than 10 articles can be published as dedicated e-books, ensuring wide and rapid dissemination.

Further information on MDPI's Special Issue polices can be found here.

Related Special Issue

Published Papers (2 papers)

Download All Papers
Order results
Result details
Show export options expand_more Show export options expand_less
Select all
Export citation of selected articles as:

Review

Jump to: Other

14 pages, 1265 KiB  
Review
Sarcoidosis, Mycobacterium paratuberculosis and Noncaseating Granulomas: Who Moved My Cheese
by Coad Thomas Dow, Nancy W. Lin and Edward D. Chan
Microorganisms 2023, 11(4), 829; https://doi.org/10.3390/microorganisms11040829 - 24 Mar 2023
Cited by 1 | Viewed by 6141
Abstract
Clinical and histological similarities between sarcoidosis and tuberculosis have driven repeated investigations looking for a mycobacterial cause of sarcoidosis. Over 50 years ago, “anonymous mycobacteria” were suggested to have a role in the etiology of sarcoidosis. Both tuberculosis and sarcoidosis have a predilection [...] Read more.
Clinical and histological similarities between sarcoidosis and tuberculosis have driven repeated investigations looking for a mycobacterial cause of sarcoidosis. Over 50 years ago, “anonymous mycobacteria” were suggested to have a role in the etiology of sarcoidosis. Both tuberculosis and sarcoidosis have a predilection for lung involvement, though each can be found in any area of the body. A key histopathologic feature of both sarcoidosis and tuberculosis is the granuloma—while the tuberculous caseating granuloma has an area of caseous necrosis with a cheesy consistency; the non-caseating granuloma of sarcoidosis does not have this feature. This article reviews and reiterates the complicity of the infectious agent, Mycobacterium avium subsp. paratuberculosis (MAP) as a cause of sarcoidosis. MAP is involved in a parallel story as the putative cause of Crohn’s disease, another disease featuring noncaseating granulomas. MAP is a zoonotic agent infecting ruminant animals and is found in dairy products and in environmental contamination of water and air. Despite increasing evidence tying MAP to several human diseases, there is a continued resistance to embracing its pleiotropic roles. “Who Moved My Cheese” is a simple yet powerful book that explores the ways in which individuals react to change. Extending the metaphor, the “non-cheesy” granuloma of sarcoidosis actually contains the difficult-to-detect “cheese”, MAP; MAP did not move, it was there all along. Full article
(This article belongs to the Special Issue Nontuberculous Mycobacteria: Emerging Diseases and Health Impacts 2.0)
►▼ Show Figures

Figure 1

Other

Jump to: Review

10 pages, 1567 KiB  
Case Report
Disseminated Mycobacterium genavense Infection Mimicking Sarcoidosis: A Case Report and Review of Literature on Japanese Patients
by Ryo Ogata, Takashi Kido, Kazuaki Takeda, Kazuki Nemoto, Riko Heima, Mami Takao, Ritsuko Miyashita, Mutsumi Ozasa, Takatomo Tokito, Daisuke Okuno, Yuya Ito, Hirokazu Yura, Tomohiro Koga, Kunio Hashimoto, Shinnosuke Takemoto, Takahiro Takazono, Hiroshi Ishimoto, Noriho Sakamoto, Kazumasa Fukuda, Yuka Sasaki, Yasushi Obase, Yuji Ishimatsu, Kazuhiro Yatera, Koichi Izumikawa and Hiroshi Mukaeadd Show full author list remove Hide full author list
Microorganisms 2023, 11(9), 2145; https://doi.org/10.3390/microorganisms11092145 - 24 Aug 2023
Cited by 1 | Viewed by 1472
Abstract
Sarcoidosis is a systemic inflammatory disease characterized by noncaseating epithelioid cell granulomas. However, certain infections can exhibit similar histological findings. We present a case of a 69-year-old man who was initially diagnosed with sarcoidosis and later was confirmed, through 16S rRNA sequencing, to [...] Read more.
Sarcoidosis is a systemic inflammatory disease characterized by noncaseating epithelioid cell granulomas. However, certain infections can exhibit similar histological findings. We present a case of a 69-year-old man who was initially diagnosed with sarcoidosis and later was confirmed, through 16S rRNA sequencing, to have disseminated Mycobacterium genavense infection. Acid-fast bacteria were detected in the bone marrow biopsy using Ziehl–Neelsen staining, but routine clinical tests did not provide a definitive diagnosis. The patient tested negative for HIV, anti-interferon-gamma antibodies, and genetic immunodeficiency disorders. He was treated with multiple drugs, including aminoglycosides and macrolides, but showed no improvement in fever and pancytopenia. However, these clinical signs responded favorably to steroid therapy. We reviewed 17 Japanese cases of M. genavense infection. All cases were in males; 7/17 (41%) were HIV-negative; and 12/17 (71%) had a decreased CD4 count. Genetic analysis confirmed M. genavense isolation, and macrolides were used universally. Mycobacterium genavense infection is challenging to identify and mimics other systemic inflammatory diseases such as sarcoidosis. There are no standard treatment protocols. Our case report and Japanese case review contribute to understanding this rare disease. Full article
(This article belongs to the Special Issue Nontuberculous Mycobacteria: Emerging Diseases and Health Impacts 2.0)
►▼ Show Figures

Figure 1

Show export options expand_more Show export options expand_less
Select all
Export citation of selected articles as:
 
Displaying articles 1-2
Back to TopTop