New Advances in Management and Treatment of Acinetobacter baumannii Infections
A special issue of Microorganisms (ISSN 2076-2607). This special issue belongs to the section "Antimicrobial Agents and Resistance".
Deadline for manuscript submissions: closed (31 December 2023) | Viewed by 3215
Special Issue Editor
Interests: septic shock; multidrug-resistant pathogens; severe infections; hospital infections; antimicrobials
Special Issues, Collections and Topics in MDPI journals
Special Issue Information
Dear Colleagues,
Infections caused by MDR Acinetobacter baumannii (MDR-AB) represent a major problem in patients admitted to hospital, especially intensive care units. Inappropriate therapy and limited therapeutic options are responsible for negative impact on outcome and this infection is associated with high mortality rates.MDR-AB has been defined one of the top priority pathogens by the World Health Organization; Acinetobacter baumannii bacteria are usually resistant to carbapenems and to β-lactams, aminoglycosides, rifampin, and fluoroquinolones. Then, there are limited therapeutic options with a subsequent negative impact on outcome. New agents with microbiological activity against MDR-AB strains have been recently developed but further real-life data are needed. Mortality rate over 60% has been reported for MDR-AB infections, particularly in patients with septic shock. Early diagnosis and adequate administration of antimicrobials are the milestone for the management of critically ill patients, and data about therapeutic approach when use monotherapy and when combination therapy, are limited. On these bases, physicians should recognize peculiar clinical characteristics and treat MDR-AB infections appropriately in hospitalized patients.This Special Issue aims to collect papers on Acinetobacter baumannii infections to better define the management and treatment of this difficult-to-treat infection. For this Special Issue, we invite to submit research articles, review articles, case series and clinical cases on the current status of Acinetobacter baumannii infections, especially in critically-ill patients.
Dr. Alessandro Russo
Guest Editor
Manuscript Submission Information
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Keywords
- Acinetobacter baumannii
- MDR
- virulence factors
- antibiotic resistance
- antibiotic therapy
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