Flaviviruses—Antivirals and Vaccines
A special issue of Microorganisms (ISSN 2076-2607). This special issue belongs to the section "Antimicrobial Agents and Resistance".
Deadline for manuscript submissions: closed (30 April 2021) | Viewed by 8458
Special Issue Editor
Special Issue Information
Dear Colleagues,
The genus Flavivirus (family Flaviviridae) is a group of small enveloped RNA viruses that are mainly transmitted by the bite of infected mosquitoes or ticks. Flaviviruses are responsible for a variety of diseases threatening both human and animal health. Climate change and the globalization of trade and travel, as well as changes in land use and urbanization, are contributing to the emergence (or re-emergence) of flaviviruses such as yellow fever, West Nile, dengue, and Zika viruses. Although there are already a few vaccines licensed for veterinary or human use, there is still a lack of vaccines for most flaviviruses. The complex biology of flaviviruses and the immunological crosstalk between them, which is responsible for the antibody-dependent enhancement of infection, are complicating the development and massive application of some vaccines (i.e., dengue). In addition, there is currently no antiviral therapy licensed for any flavivirus. Therefore, the development of safe and cost-affordable vaccines and antivirals constitute research priorities to combat these pathogens. These goals will only be achieved by joining efforts from multiple disciplines including virology, cell biology, epidemiology, clinicians, entomologists, immunologists, medicinal chemists, etc.
The aim of this Special Issue is to provide an adequate multidisciplinary platform for the interchange of valuable information (both basic and applied research) that aids the development of efficient vaccines and antiviral therapies against flaviviruses.
As a Guest Editor of the Special Issue, I invite you to submit research articles, review articles, and short communications related to flavivirus biology and infection, vaccine development, and antiviral discovery.
Dr. Miguel A. Martín-Acebes
Guest Editor
Manuscript Submission Information
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Keywords
- flavivirus
- vaccine
- antiviral
- infection
- antibody-dependent enhancement of infection
- dengue virus
- West Nile virus
- Zika virus
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