State-of-the-Art Gut Microbiota Research in France

Dear Colleagues,

This Special Issue of Microorganisms will give an overview of current gut microbiota research being performed in France, both in fundamental (CNRS) and applied host institutions (INSERM, CEA, INRAe), and with a particular focus on the impact of this research for human health perspectives. Current studies on how microbes influence host physiology and pathologies mostly rely on the taxonomic profiling of the gut microbiota from mouth to anus, communities living close to the mucosa and in the lumen, and in different pathological situations. However, there are still important gaps in our understanding of the causal relationship between alterations in the microbiota (i.e., dysbiosis) and disease initiation/progression, hence studies or reviews tackling this question will be welcomed in this Special Issue. Moreover, studies aiming at understanding with an ecological perspective how microbial communities interact with each other and their host environment represent an exciting research direction for the future, and will also be invited. In this Special Issue entitled “State-of-the-Art Gut Microbiota Research in France” we invite colleagues to contribute original research articles or reviews related to their multidisciplinary research, on topics including, but not limited to, the following:

• Biologically relevant host–microbiota models, from in vitro to in vivo and ex vivo;
• Structure and function of the microbiota;
• Microbial community genetics, transcriptomics, proteomics and metabolomics;
• Microbe–microbe interaction within host-associated microbial communities;
• Metabolic interaction with the host;
• Inflammatory diseases;
• Interaction with the immune system;
• Microbial biodegradation of nutrients and xenobiotics: role in drug response;
• Microbial ecology;
• Microbial biofilms interacting with host mucosa;
• Microbial biogeography;
• Microbial functions in the different habitats within the gut;
• Metabolic flux analysis;
• Analysis of functionalities by stable isotope probing (DNA, RNA, and protein);
• Model systems for studying microbiome biology;
• Novel technologies for the analysis of structure and function of the microbiota.

Dr. Jean-Paul Motta
Guest Editor

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