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Microorganisms
Special Issues
Innovating the Prevention, Control and Treatment of Respiratory Viral Infections...
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Innovating the Prevention, Control and Treatment of Respiratory Viral Infections in Children and Adolescents

A special issue of Microorganisms (ISSN 2076-2607). This special issue belongs to the section "Medical Microbiology".

Deadline for manuscript submissions: closed (30 April 2022) | Viewed by 2466

Special Issue Editor

Prof. Dr. Barbara Rath

E-Mail Website
Guest Editor
1. Vienna Vaccine Safety Initiative, Berlin, Germany
2. School of Medicine, University of Nottingham, Nottingham, UK
Interests: pediatric infection; respiratory virus; viral infections; vaccines

Special Issue Information

Dear Colleagues,

Respiratory viral infections are as common in the pediatric age group, as they are difficult to manage in the hospital, outpatient, school and community setting. This Special Issue is dedicated to forward-thinking science and technology, aimed at improving the prevention, control and treatment of respiratory viral infections in children and adolescents.

We invite innovative manuscripts describing original (clinical) research and quality improvement programs, as well as studies investigating gaps in the current state of the art, including epidemiological and meta-analyses. Preference will be given to articles introducing novel interdisciplinary approaches to the timely identification of emerging viruses and variants, to the introduction of novel antivirals and vaccines in the pediatric age group, as well as digital tools, medical devices, diagnostic tests/algorithms and machine learning/ AI methodologies facilitating the clinical management and individualized care for pediatric respiratory infections.

Prof. Dr. Barbara Rath
Guest Editor

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Microorganisms is an international peer-reviewed open access monthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2700 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • respiratory viral infections
  • epidemiology
  • pediatric infections
  • vaccines
  • prevention
  • control
  • treatment

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Further information on MDPI's Special Issue polices can be found here.

Published Papers (1 paper)

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Research

11 pages, 280 KiB  
Article
Impact of COVID-19 Infection on Children and Adolescents after Liver Transplantation in a Latin American Reference Center
by Aline F. Freitas, Renata P. S. Pugliese, Flavia Feier, Irene K. Miura, Vera Lúcia B. Danesi, Eliene N. Oliveira, Adriana P. M. Hirschfeld, Cristian B. V. Borges, Juliana V. Lobato, Gilda Porta, João Seda-Neto and Eduardo A. Fonseca
Microorganisms 2022, 10(5), 1030; https://doi.org/10.3390/microorganisms10051030 - 15 May 2022
Cited by 5 | Viewed by 1951
Abstract
Background: The COVID-19 infection has received the attention of the scientific community due to its respiratory manifestations and association with evolution to severe acute respiratory syndrome (SARS-CoV-2). There are few studies characterizing SARS-CoV-2 in pediatric immunocompromised patients, such as liver transplanted patients. The [...] Read more.
Background: The COVID-19 infection has received the attention of the scientific community due to its respiratory manifestations and association with evolution to severe acute respiratory syndrome (SARS-CoV-2). There are few studies characterizing SARS-CoV-2 in pediatric immunocompromised patients, such as liver transplanted patients. The aim of this study was to analyze the outcomes of the largest cohort of pediatric liver transplant recipients (PLTR) from a single center in Brazil who were infected with COVID-19 during the pandemic. Methods: Cross-sectional study. Primary outcomes: COVID-19 severity. The Cox regression method was used to determine independent predictors associated with the outcomes. Patients were divided into two groups according to the severity of COVID-19 disease: moderate–severe COVID and asymptomatic–mild COVID. Results: Patients categorized as having moderate–severe COVID-19 were younger (12.6 months vs. 82.1 months, p = 0.03), had a higher prevalence of transplantation from a deceased donor (50% vs. 4.3%, p = 0.02), and had a higher prevalence of COVID infection within 6 months after liver transplantation (LT) (75% vs. 5.7%, p = 0.002). The independent predictor of COVID-19 severity identified in the multivariate analysis was COVID-19 infection <6 months after LT (HR = 0.001, 95% CI = 0.001–0.67, p = 0.03). Conclusion: The time interval of less than 6 months between COVID-19 infection and LT was the only predictor of disease severity in pediatric patients who underwent liver transplantation. Full article
(This article belongs to the Special Issue Innovating the Prevention, Control and Treatment of Respiratory Viral Infections in Children and Adolescents)
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