Peptides and Peptide Mimetics: Design, Synthesis, and Applications
A special issue of Molecules (ISSN 1420-3049). This special issue belongs to the section "Cross-Field Chemistry".
Deadline for manuscript submissions: 31 July 2025 | Viewed by 25
Special Issue Editor
Interests: developing novel organelle-targeting strategies for precise delivery of bioimaging and therapeutic agents
Special Issues, Collections and Topics in MDPI journals
Special Issue Information
Dear Colleagues,
Molecules invites submissions for a Special Issue on "Peptides and Peptide Mimetics: Design, Synthesis, and Applications". This Special Issue aims to showcase the latest advancements in the design, synthesis, and innovative applications of peptides and peptide mimetics across various fields, including medicinal chemistry, drug development, and biotechnology. Peptides and peptide mimetics have garnered significant attention due to their versatility, specificity, and potential to modulate biological pathways. This Special Issue will focus on groundbreaking research in the synthesis of novel peptides and peptide-like molecules, advances in peptide modification techniques, and the development of bioactive peptides for therapeutic applications. We welcome original research articles, reviews, and short communications on topics including, but not limited to:
- Peptide Design and Synthesis: Novel strategies for synthesizing bioactive peptides, including solid-phase and solution-phase synthesis, and new methods for peptide modification.
- Peptide Mimetics: Development of peptide-like compounds with enhanced stability, bioavailability, and efficacy, including peptoids, foldamers, and other mimetics.
- Therapeutic Applications: Design and evaluation of peptides and peptide mimetics as potential therapeutics in cancer, infectious diseases, metabolic disorders, and neurological conditions.
- Peptide-Based Drug Delivery Systems: Advances in using peptides as vehicles for targeted drug delivery, including self-assembling peptides, cell-penetrating peptides, and receptor-targeting peptides. Biotechnological Applications: Novel uses of peptides and mimetics in biotechnology, including biosensors, diagnostics, and as tools for molecular imaging.
- Structure–Activity Relationship (SAR) Studies: Elucidating SARs of bioactive peptides and mimetics to optimize efficacy and selectivity. Computational Approaches: The role of computational chemistry in peptide design, molecular modeling, and predicting peptide interactions with biological targets.
All submissions will undergo a rigorous peer-review process to ensure the highest quality of published research. We encourage authors from academia, industry, and interdisciplinary research fields to contribute to this Special Issue, which aims to provide a comprehensive overview of current trends and future directions in peptide science. We look forward to your contributions to this exciting issue.
Dr. Lanrong Bi
Guest Editor
Manuscript Submission Information
Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.
Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Molecules is an international peer-reviewed open access semimonthly journal published by MDPI.
Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2700 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.
Keywords
- peptide design
- peptide mimetics
- bioactive peptides
- peptide synthesis
- therapeutic peptides
- drug delivery systems
- peptide-based biotechnology
- structure–activity relationship (SAR)
- computational peptide modeling
- peptoids and foldamers
Benefits of Publishing in a Special Issue
- Ease of navigation: Grouping papers by topic helps scholars navigate broad scope journals more efficiently.
- Greater discoverability: Special Issues support the reach and impact of scientific research. Articles in Special Issues are more discoverable and cited more frequently.
- Expansion of research network: Special Issues facilitate connections among authors, fostering scientific collaborations.
- External promotion: Articles in Special Issues are often promoted through the journal's social media, increasing their visibility.
- e-Book format: Special Issues with more than 10 articles can be published as dedicated e-books, ensuring wide and rapid dissemination.
Further information on MDPI's Special Issue polices can be found here.
