Harnessing Antioxidants: Pioneering Approaches in Cardiovascular Disease Prevention and Therapy
A special issue of Antioxidants (ISSN 2076-3921). This special issue belongs to the section "Health Outcomes of Antioxidants and Oxidative Stress".
Deadline for manuscript submissions: 10 May 2025 | Viewed by 515
Special Issue Editors
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Interests: diabetes; insulin; pancreatic beta cell; artificial pancreas system; glucose-insulin homeostasis
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Special Issue Information
Dear Colleagues,
The significant impact of oxidative stress on the pathophysiology of cardiovascular diseases (CVDs) underscores a complex interplay between the production of reactive oxygen species (ROS) and the body's antioxidant defenses. Notably, the heart, with its considerable metabolic requirements, presents comparatively lower antioxidant capacities than other organs, rendering it exceptionally vulnerable to oxidative insults. This susceptibility is implicated in a range of cardiovascular pathologies, including hypertrophy, cardiomyopathy, and myocardial infarction. Traditionally perceived as detrimental, free radicals are now recognized for their potential roles in cellular signaling processes, a paradigm shift that has improved our understanding of their biological implications. This evolving perspective has yielded heterogeneous outcomes in studies assessing antioxidant therapies for myocardial protection, occasionally indicating deleterious effects when attempting to modulate systemic levels of ROS.
In light of these complexities, this Special Issue titled "Harnessing Antioxidants: Pioneering Approaches in Cardiovascular Disease Prevention and Therapy" seeks to critically examine and elucidate the dualistic roles of antioxidants in cardiovascular health. Our objective is to reassess and broaden our comprehension of how both naturally derived and synthetically formulated antioxidants can alter the functional and structural trajectories of CVD. We invite contributions that present cutting-edge antioxidant strategies, provide detailed mechanistic insights, and report findings from rigorous clinical trials aimed at optimizing the modulation of oxidative stress within the cardiovascular domain.
We encourage the submission of original research and comprehensive review articles to this Special Issue. Each manuscript should significantly enhance our collective understanding of the sophisticated mechanisms by which antioxidants can be strategically leveraged in the prevention and treatment of cardiovascular diseases, effectively bridging the divide between fundamental research and clinical practice.
As Guest Editors, we look forward to receiving your scholarly contributions, which will undoubtedly enrich this critical area of cardiovascular research and extend our knowledge of the potent therapeutic capabilities of antioxidants in the realm of cardiovascular health.
Dr. Lanrong Bi
Prof. Dr. Guim Kwon
Guest Editors
Manuscript Submission Information
Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.
Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Antioxidants is an international peer-reviewed open access monthly journal published by MDPI.
Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2900 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.
Keywords
- oxidative stress
- reactive oxygen species (ROS)
- antioxidants
- cardiovascular diseases
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