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Advances in and Applications of Calixarenes

A special issue of Molecules (ISSN 1420-3049). This special issue belongs to the section "Organic Chemistry".

Deadline for manuscript submissions: closed (31 December 2020) | Viewed by 2810

Special Issue Editors


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Guest Editor
School of Pharmacy and Bioengineering, Keele University, Staffordshire ST5 5BG, UK
Interests: nanopharmaceutics; nanomedicine; organic chemistry; medicinal chemistry; Calix[n]arenes; Calix[4]resorcinarenes

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Co-Guest Editor
School of Pharmacy and Biomolecular Sciences, University of Brighton, Brighton, UK
Interests: supramolecular chemistry; computational chemistry; sensors; Calix[n]arenes; Oxacalix3arene; Pillar5arenes
Special Issues, Collections and Topics in MDPI journals

E-Mail Website
Co-Guest Editor
School of Pharmacy, University of East Anglia, Norwich Research Park, Norwich, Norfolk NR4 7TJ, UK
Interests: Molecular Pharmaceutics; Macrocyclic Drugs; Topological Drugs

Special Issue Information

Dear Colleagues,

The topic of this Special Issue encompasses the various groups of compounds that are known collectively as calixarenes. They are all cyclic oligomers which can exist in a calyx-like conformation that possesses a typically hydrophobic interior cavity. After a surge of interest in calix[n]arene and calix[4]resorcinarene chemistry, which resulted in the development of many functional molecules and supramolecular assemblies, cavitands, and carceplexes as examples, calixarenes have continued to be at the core of much research. Synthetic methods which expand the range of calixarenes available, investigations into the properties of calixarenes and their supramolecular assemblies in aqueous media, and applications in therapeutics and environmental chemistry have attracted particular interest. Authors are therefore invited to submit manuscripts which relate to any aspect of advances in and the applications of compounds that fall within the broad category of calixarenes and their functionalized derivatives.

Dr. Anthony D.M. Curtis
Dr. Peter Cragg
Dr. Susan E. Matthews
Guest Editors

Manuscript Submission Information

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Keywords

  • Calixarene compounds
  • Calix[n]arenes
  • Calix[4]resorcinarenes (resorcinarenes)
  • Heterocyclic calixarenes
  • Synthetic methods
  • Macromolecular materials
  • Supramolecular chemistry
  • Nanotechnology
  • Medicine and therapeutics
  • Drug formulation
  • Bio-inspired materials
  • Catalysis
  • Environmental chemistry

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Published Papers (1 paper)

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Research

13 pages, 1367 KiB  
Article
Synthesis of Polyfluorinated Thia- and Oxathiacalixarenes Based on Perfluoro-m-xylene
by Vladimir N. Kovtonyuk, Yuri V. Gatilov, Pavel V. Nikul’shin and Roman A. Bredikhin
Molecules 2021, 26(3), 526; https://doi.org/10.3390/molecules26030526 - 20 Jan 2021
Cited by 3 | Viewed by 2115
Abstract
Perfluorinated tetrathiacalix[4]arene was obtained by heating perfluoro-m-xylene with thiourea or 2,5-difluoro-4,6-bis(trifluoromethyl)benzene-1,3-dithiol at 90 °C. Interaction of perfluoro-m-xylene with resorcinol or orcinol under mild conditions and subsequent heating of the mixture with 2,5-difluoro-4,6-bis(trifluoromethyl)benzene-1,3-dithiol leads to polyfluorinated dioxadithiacalix[4]arenes. Triphenyl and pentaphenyl [...] Read more.
Perfluorinated tetrathiacalix[4]arene was obtained by heating perfluoro-m-xylene with thiourea or 2,5-difluoro-4,6-bis(trifluoromethyl)benzene-1,3-dithiol at 90 °C. Interaction of perfluoro-m-xylene with resorcinol or orcinol under mild conditions and subsequent heating of the mixture with 2,5-difluoro-4,6-bis(trifluoromethyl)benzene-1,3-dithiol leads to polyfluorinated dioxadithiacalix[4]arenes. Triphenyl and pentaphenyl ethers formed by the interaction of perfluoro-m-xylene with resorcinol under heating with thiourea gives polyfluorinated oxathiacalixarenes containing six and five aromatic nuclei, respectively. Full article
(This article belongs to the Special Issue Advances in and Applications of Calixarenes)
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