Design and Synthesis of Novel Drugs for the Treatment of Cancer
A special issue of Molecules (ISSN 1420-3049). This special issue belongs to the section "Medicinal Chemistry".
Deadline for manuscript submissions: closed (31 December 2023) | Viewed by 3244
Special Issue Editor
Interests: metal-catalyzed reactions (cross-couplings, C-H activation, and carbonylations); nucleophilic aromatic substitution; heterocycles of N and/or S; antitumoral compounds
Special Issues, Collections and Topics in MDPI journals
Special Issue Information
Dear colleagues,
Cancer treatment is still a very demanding, important issue in human health, and during the last few years, there has been continuous progress in the development of anticancer drugs.
The overexpression of some proteins of known 3D structures, such as transmembrane receptors with intracellular enzymatic domains and others, makes them special targets in cancer cells, promoting the design and discovery of new drugs, using structure-based drug design (SBDD) that can minimize the effects of toxicity on healthy cells. Multidrug resistance (MDR) in cancer treatment is also an important problem to overcome.
In this Special Issue, researchers can share their experiences and discoveries in this promising field focused on the design and development of new potential anticancer molecules, including the biological studies performed.
Contributions to this issue may cover all aspects of new discovery and development of novel therapeutic agents for cancer.
Prof. Dr. Maria João Queiroz
Guest Editor
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