Modern Isolation Techniques in the Recovery of Bioactive Natural Products from Plant Matrices
A special issue of Molecules (ISSN 1420-3049). This special issue belongs to the section "Natural Products Chemistry".
Deadline for manuscript submissions: closed (31 January 2023) | Viewed by 5973
Special Issue Editors
Interests: natural products chemistry; chromatography; mass spectrometry; bioactivity testing; secondary metabolites
Special Issues, Collections and Topics in MDPI journals
Interests: phytochemicals; bioactivity antioxidant activity; chromatography extraction; food chemistry; mass spectrometry; antioxidants; natural product chemistry; antibacterial activity
Interests: green chemistry and large-scale extraction of high added-value natural products; isolation of natural products leads; identification and structural elucidation of natural products; semi- and total synthesis of natural products; characterization of natural extracts; design and synthesis of new molecules with pharmacological interest; structure–activity relationships
Special Issues, Collections and Topics in MDPI journals
Special Issue Information
Dear Colleagues,
Plant extracts are rich sources of natural products of differing chemical characteristics and structures. Many of them have been commonly used in the traditional medicine around the world to heal various types of ailments. Still, these days primary and secondary metabolites of plant origin have a function of drugs or scaffoldings for the semi-synthesis of new, often more active, pharmaceuticals.
That is why the necessity to perform isolation and identification studies of the extracts’ constituents is of the highest importance. Single molecules with confirmed bioactivity can be better validated in terms of their toxicity, active doses, mechanisms of action, interactions with other drugs, or stability. The recent development of analytical equipment with high measurement accuracy and selectivity provides better chances for the isolation of natural products. On the other hand, a wide range of in vitro and in vivo assays are able to trace promising compounds―drug candidates of different kind―in the total extracts.
This Special Issue will present interdisciplinary manuscripts covering the application of modern extraction and isolation techniques in the recovery of pharmacologically potent metabolites.
Prof. Wirginia Kukula-Koch
Dr. Apostolis Angelis
Prof. Alexios Leandros Skaltsounis
Guest Editors
Manuscript Submission Information
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Keywords
- extraction and isolation
- plant extracts
- metabolites
- natural products
- identification and structure elucidation
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