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Nanotechnology for Bio-Detection

A special issue of Molecules (ISSN 1420-3049). This special issue belongs to the section "Analytical Chemistry".

Deadline for manuscript submissions: closed (28 February 2020) | Viewed by 3609

Special Issue Editors


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Guest Editor
College of Electronic Information and Optical Engineering, Nankai University, Tianjin 300071, China
Interests: graphene-based field-effect transistors; solution gate; sensors; memristors; neuromorphic computing; synaptic devices
Special Issues, Collections and Topics in MDPI journals

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Guest Editor
Department of Electrical and Biomedical Engineering, University of Nevada Reno, Reno, NV 89557, USA
Interests: luminescence materials; nanoparticles; biosensing; trace gas sensing; instrumentation
Special Issues, Collections and Topics in MDPI journals

Special Issue Information

Dear Colleagues,

This Special Issue is proposed to encourage further research and development in nanotechnologies in the field of bio-detection.

Nanotechnology is generally defined as the manipulation of matter with at least one dimension sized from 1 to 100 nanometers. It is an interdisciplinary and comprehensive research area, which involves not only the traditional micro/nano manufacturing science and technology, such as molecular beam epitaxy, high-precision lithography, ion beam milling, etc., but also the recently developed techniques of molecular tailoring and assembly to fabricate the so-called molecular devices, 2D nano-materials (like graphene), functional nucleic acid-functionalized sensing interfaces, nano/quantum-particle-enhanced biosensors, and so on.

Nanotechnology for bio-detection is one of the branches of the numerous applications of nanotechnology. Thanks to intriguing nanotechnology studies such as those on lab-on-chip, functional nanomaterials, 3D/2D nanomaterial-enhanced bio-sensing interfaces and biosensors, fast and cheaper bio-assays can be realized. This Special Issue will cover a wide range of topics related to nanotechnology in bio-detection, like nano-biomimetics-generated novel sensing strategies, graphene- or other 2D nanomaterial-based biosensors, quantum dot-constructed in vivo biosensors or bio-sensing interfaces, functional nucleic acid-based biosensors, etc.. Contributions to this Special Issue might be perspectives, reviews, or original researches.

Prof. Dr. Yunfang Jia
Prof. Dr. Xiaoshan Zhu
Guest Editors

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Keywords

  • nano-biosensor
  • in vivo nano-imaging sensor
  • quantum dot or nanoparticle-based biosensor
  • graphene
  • nanozyme
  • molecular tailoring
  • molecular device
  • functional nucleic acid
  • porphyrins
  • on-chip bio-detection

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Published Papers (1 paper)

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Research

9 pages, 1663 KiB  
Article
Synthesis of Nano-Praseodymium Oxide for Cataluminescence Sensing of Acetophenone in Exhaled Breath
by Qian-Chun Zhang, Wu-Li Yan, Li Jiang, Yu-Guo Zheng, Jing-Xin Wang and Run-Kun Zhang
Molecules 2019, 24(23), 4275; https://doi.org/10.3390/molecules24234275 - 23 Nov 2019
Cited by 18 | Viewed by 3319
Abstract
In this work, we successfully developed a novel and sensitive gas sensor for the determination of trace acetophenone based on its cataluminescence (CTL) emission on the surface of nano-praseodymium oxide (nano-Pr6O11). The effects of working conditions such as temperature, [...] Read more.
In this work, we successfully developed a novel and sensitive gas sensor for the determination of trace acetophenone based on its cataluminescence (CTL) emission on the surface of nano-praseodymium oxide (nano-Pr6O11). The effects of working conditions such as temperature, flow rate, and detecting wavelength on the CTL sensing were investigated in detail. Under the optimized conditions, the sensor exhibited linear response to the acetophenone in the range of 15–280 mg/m3 (2.8–52 ppm), with a correlation coefficient (R2) of 0.9968 and a limit of detection (S/N = 3) of 4 mg/m3 (0.7 ppm). The selectivity of the sensor was also investigated, no or weak response to other compounds, such as alcohols (methanol, ethanol, n-propanol, iso-propanol, n-butanol), aldehyde (formaldehyde and acetaldehyde), benzenes (toluene, o-xylene, m-xylene, p-xylene), n-pentane, ethyl acetate, ammonia, carbon monoxide, carbon dioxide. Finally, the present sensor was applied to the determination of acetophenone in human exhaled breath samples. The results showed that the sensor has promising application in clinical breath analysis. Full article
(This article belongs to the Special Issue Nanotechnology for Bio-Detection)
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