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Organic Electrochemistry 2019

A special issue of Molecules (ISSN 1420-3049). This special issue belongs to the section "Electrochemistry".

Deadline for manuscript submissions: closed (31 December 2019) | Viewed by 8501

Special Issue Editor


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Guest Editor
A.E.Arbuzov Institute of Organic and Physical Chemistry of RAS, Kazan, Russia
Interests: electrochemistry; organic chemistry; electrosynthesis; electroanalysis; electrocatalytic phenomena; physical chemistry; catalysis; redox processes; electron transfer; intermediates; metal complex catalysis; coupling reactions; functionalization; green chemistry; organoelemental compounds

Special Issue Information

Dear Colleagues,

Organic electrochemistry is now developing as an integrating area, including not only organic electrosynthesis but also material chemistry, catalytic chemistry, biochemistry, medical chemistry, and environmental chemistry. The principles of electrochemistry are widely used in organic synthesis. Organic electrochemistry involves the activation of organic molecules by transferring electrons from or to the electrode surface. In the process, it is possible to obtain a variety of new products, to study the redox properties of substances, and to realize a variety of transformations, where oxidation or reduction is the key stage. An important aspect of the electrochemical methodology is that many electrochemical processes meet the requirements of ecological cleanness. Indeed, electrochemical reactions have a number of advantages: the mild conditions of their flow, high rates, the selectivity of the process, as well as convenient operational control using parameters such as current density and potential. It is easy to automate the control of electrochemical processes. Electrochemical methods can be recommended for preventive protection of the environment since special reagents are not required.

This Special Issue aims to demonstrate and review the latest achievements in the field of organic electrochemistry, including new examples of electrochemical reactions in the context of the synthesis of complex molecules; electrochemical, efficient, and atom-economical methods for the formation of new bonds; new catalytic approaches that combine electrochemistry and redox-metal catalysis including small-molecule activation, biomimetic electrochemical reactions, radical and ionic transformations induced electrochemically, mechanism recognition, as well as various practical applications; and the fundamental issues of organic electrochemistry.

Prof. Yulia H. Budnikova
Guest Editor

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Keywords

  • Organic electrosynthesis
  • Electrocatalytic phenomena
  • Electron transfer
  • Electroanalysis
  • Green chemistry
  • Mechanism of electrochemical reaction
  • Mediators
  • Applied organic electrochemistry
  • Biomimetic electrochemical catalysis

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Published Papers (2 papers)

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Research

12 pages, 1455 KiB  
Article
Evaluation of Transition Metal Catalysts in Electrochemically Induced Aromatic Phosphonation
by Sofia Strekalova, Mikhail Khrizanforov and Yulia Budnikova
Molecules 2019, 24(9), 1823; https://doi.org/10.3390/molecules24091823 - 11 May 2019
Cited by 7 | Viewed by 3841
Abstract
Voltammetry provides important information on the redox properties of catalysts (transition metal complexes of Ni, Co, Mn, etc.) and their activity in electrocatalytic reactions of aromatic C–H phosphonation in the presence of a phosphorus precursor, for example, dialkyl-H-phosphonate. Based on catalytic [...] Read more.
Voltammetry provides important information on the redox properties of catalysts (transition metal complexes of Ni, Co, Mn, etc.) and their activity in electrocatalytic reactions of aromatic C–H phosphonation in the presence of a phosphorus precursor, for example, dialkyl-H-phosphonate. Based on catalytic current growth of oxidation or reduction of the metal catalysts (CoII, MnII, NiII, MnII/NiII, MnII/CoII, and CoII/NiII), quantitative characteristics of the regeneration of catalysts were determined, for example, for MnII, NiII and MnII/NiII, CoII/NiII pairs. Calculations confirmed the previously made synthetic observations on the synergistic effect of certain metal ions in binary catalytic systems (MnIIbpy/NiIIbpy and NiIIbpy/CoIIbpy); for mixtures, the observed rate constants, or TOF, were 690 s−1 and 721 s−1, respectively, and product yields were higher for monometallic catalytic systems (up to 71% for bimetallic catalytic systems and ~30% for monometallic catalytic systems). In some cases, the appearance of pre-waves after adding H-phosphonates confirmed the preceding chemical reaction. It also confirmed the formation of metal phosphonates in the time scale of voltammetry, oxidizing or reducing at lower potentials than the original (RO)2P(O)H and metal complex, which could be used for fast diagnostics of metal ion and dialkyl-H-phosphonate interactions. Electrochemical transfer of an electron to (from) metal phosphonate generates a phosphonyl radical, which can then react with different arenes to give the products of aromatic C–H phosphonation. Full article
(This article belongs to the Special Issue Organic Electrochemistry 2019)
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10 pages, 2363 KiB  
Article
High Sensitive Immunoelectrochemical Measurement of Lung Cancer Tumor Marker ProGRP Based on TiO2-Au Nanocomposite
by Zheng Wei, Xiaoping Cai, Junping Zhang, Junming Fan, Jiangyan Xu and Liran Xu
Molecules 2019, 24(4), 656; https://doi.org/10.3390/molecules24040656 - 13 Feb 2019
Cited by 18 | Viewed by 4184
Abstract
Progastrin-releasing peptide (ProGRP), which is known to be highly specific and sensitive to small cell lung cancer (SCLC), has been proven to be a valuable substitute for neuron-specific enolase in SCLC diagnostics and monitoring, especially in its early stages. The detection of ProGRP [...] Read more.
Progastrin-releasing peptide (ProGRP), which is known to be highly specific and sensitive to small cell lung cancer (SCLC), has been proven to be a valuable substitute for neuron-specific enolase in SCLC diagnostics and monitoring, especially in its early stages. The detection of ProGRP levels also facilitates a selection of therapeutic treatments. For the fabrication of our proposed biosensor, titanium (IV) oxide microparticles were first used, followed by dispersing gold nanoparticles into chitosan and immobilizing them onto a carbon paste electrode (CPE) surface. The developed immunosensor exhibits a much higher biosensing performance in comparison with current methods, when it comes to the detection of ProGRP. Therefore, the proposed CPE/TiO2/(CS+AuNPs)/anti-ProGRP/BSA/ProGRP is excellent for the development of a compact diagnostics apparatus. Full article
(This article belongs to the Special Issue Organic Electrochemistry 2019)
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