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Synthesis and Application of Ester Derivatives

A special issue of Molecules (ISSN 1420-3049). This special issue belongs to the section "Organic Chemistry".

Deadline for manuscript submissions: closed (30 May 2022) | Viewed by 4405

Special Issue Editor


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Guest Editor
State Key Laboratory of Chemo/Biosensing and Chemometrics, Advanced Catalytic Engineering Research Center of the Ministry of Education, College of Chemistry and Chemical Engineering, Institute of Shenzhen, Hunan University, Changsha 410082, China
Interests: organic chemistry; organometallic chemistry; antimony chemistry; boron chemistry; C–H functionalization; photocatalysis
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Special Issue Information

Dear Colleagues,

The chemistry of esterification is recognized as a mainstay in modern organic synthesis. Esters are ubiquitous in natural products, pharmaceuticals, fine chemicals, polymer materials and many more. Esters of carboxylic acids are ubiquitous not only as useful synthetic precursors in organic synthesis but also as important building blocks in pharmaceuticals and agrochemicals. Esters are commonly occurring structural motifs that are finding increasing applications in medicinal chemistry owing to their diverse bioactivities.

This Special Issue aims to present recent advances in ester chemistry, from the development of new synthetic methods (catalyst, thermal catalysis, photocatalysis, electrocatalysis, Lewis acid catalysis, transition metal catalysis, microwave catalysis, C-H activation, etc. ), important derivatives (steroids, carbonate ester, etc.), the study of their properties (electronic, optical, biological, etc.), to their use in a broad range of fields, including materials, medicinal chemistry, analytical chemistry, etc.

We welcome communications, full research articles, and reviews on topics related to these fields.

Prof. Dr. Renhua Qiu
Guest Editor

Manuscript Submission Information

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Keywords

  • Esters
  • Esterification
  • New synthetic methods
  • C-H activation
  • Photocatalysis
  • Radical reactions
  • Medicinal chemistry
  • Materials
  • Polymers
  • Fine chemicals
  • Biological properties

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Published Papers (1 paper)

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Research

15 pages, 645 KiB  
Article
Quinine Esters with 1,2-Azole, Pyridine and Adamantane Fragments
by Gulim K. Mukusheva, Aigerym R. Zhasymbekova, Roza B. Seidakhmetova, Oralgazy A. Nurkenov, Ekaterina A. Akishina, Sergey K. Petkevich, Evgenij A. Dikusar and Vladimir I. Potkin
Molecules 2022, 27(11), 3476; https://doi.org/10.3390/molecules27113476 - 27 May 2022
Cited by 1 | Viewed by 2242
Abstract
An efficient method of producing quinine derivatives via reaction of acylation with 4,5-dichloroisothiazole-3-, 5-arylisoxazole-3-, adamantane- and hydrochlorides of pyridine-3- and pyridine-4-carbonyl chlorides was developed. All synthesized compounds were tested for antiviral, antimicrobial and analgesic activity. The most pronounced antibacterial activity was shown by [...] Read more.
An efficient method of producing quinine derivatives via reaction of acylation with 4,5-dichloroisothiazole-3-, 5-arylisoxazole-3-, adamantane- and hydrochlorides of pyridine-3- and pyridine-4-carbonyl chlorides was developed. All synthesized compounds were tested for antiviral, antimicrobial and analgesic activity. The most pronounced antibacterial activity was shown by the compounds 2e, 3b, 3c and 3e with isoxazole and pyridine fragments. It was found that most of the tested compounds showed significant analgesic activity reducing the pain response of animals to the irritating effect of acetic acid. Full article
(This article belongs to the Special Issue Synthesis and Application of Ester Derivatives)
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