Immune Responses to Pulmonary Pathogens

A special issue of Pathogens (ISSN 2076-0817). This special issue belongs to the section "Immunological Responses and Immune Defense Mechanisms".

Deadline for manuscript submissions: closed (31 August 2024) | Viewed by 1227

Image courtesy of The image was created using Biorender.com.

Special Issue Editors


E-Mail Website
Guest Editor
National Institute of Allergy and Infectious Diseases (NIAID), Bethesda, MD 20814, USA
Interests: Mycobacteria; Bacillus anthracis; antibody engineering; omics; bacterial signaling

E-Mail Website
Guest Editor
National Cancer Institute, NIH, Bethesda, MD 20814, USA
Interests: pharmacology; drug resistance; nucleotide vaccines; immunology
Special Issues, Collections and Topics in MDPI journals

E-Mail Website
Guest Editor
Renaissance School of Medicine, State University of New York, Stony Brook, NY 11794, USA
Interests: cell envelope; proteomics; proximity labeling; host pathogen interaction; immunometabolism; lipidomics; secretion systems; lipid transport

Special Issue Information

Dear Colleagues,

We are pleased to announce the forthcoming Special Issue entitled “Immune Responses to Pulmonary Pathogens”. This Special Issue aims to explore the field of host immune responses to pulmonary pathogens, encompassing a range of bacterial infections, including Mycobacteria, Bacillus anthracis, Streptococci and more. We welcome researchers studying these diverse bacterial pathogens to contribute their research to this Special Issue of Pathogens.

Pulmonary pathogens pose significant challenges to global health. Understanding the interaction between bacteria and the host immune system is crucial for developing effective strategies for diagnosis, treatment and prevention. This Special Issue provides an opportunity to present and exchange research findings related to the immune responses of the host, as well as the mechanisms of host immune evasion of pathogenic bacteria that infect pulmonary organs.

Contributions to this Special Issue can cover a wide range of topics, including, but not limited to:

  • Molecular mechanisms of bacterial invasion and colonization in pulmonary organs;
  • Host immune responses against bacterial infections;
  • Bacterial immune evasion strategies;
  • Immunopathogenesis and disease progression in bacterial infections;
  • Novel therapeutic approaches and vaccine development against pulmonary bacterial pathogens;
  • Post-COVID host responses to pulmonary pathogens. 

This Special Issue aims to foster a comprehensive understanding of bacterial immunology by gathering research on different pulmonary pathogens. Researchers from diverse disciplines, including immunology, microbiology, infectious diseases and clinical research, are invited to actively participate and contribute their expertise to submit their original research papers, clinical data, meta-analysis and review articles to this Special Issue of Pathogens. Together, let us advance our knowledge in host immune responses to pulmonary bacterial infections, along with their combat strategies. 

Dr. Ankur Bothra
Dr. Andaleeb Sajid
Dr. Neetika Jaisinghani
Guest Editors

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Pathogens is an international peer-reviewed open access monthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2200 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • Mycobacteria
  • Bacillus anthracis
  • Pseudomonas aeruginosa
  • Staphylococcus aureus
  • immune response
  • virulence and pathogenesis
  • drug design
  • vaccine strategies

Benefits of Publishing in a Special Issue

  • Ease of navigation: Grouping papers by topic helps scholars navigate broad scope journals more efficiently.
  • Greater discoverability: Special Issues support the reach and impact of scientific research. Articles in Special Issues are more discoverable and cited more frequently.
  • Expansion of research network: Special Issues facilitate connections among authors, fostering scientific collaborations.
  • External promotion: Articles in Special Issues are often promoted through the journal's social media, increasing their visibility.
  • e-Book format: Special Issues with more than 10 articles can be published as dedicated e-books, ensuring wide and rapid dissemination.

Further information on MDPI's Special Issue polices can be found here.

Published Papers (1 paper)

Order results
Result details
Select all
Export citation of selected articles as:

Research

10 pages, 415 KiB  
Article
Deciphering the Longevity and Levels of SARS-CoV-2 Antibodies in Children: A Year-Long Study Highlighting Clinical Phenotypes and Age-Related Variations
by Gemma Pons-Tomàs, Rosa Pino, Aleix Soler-García, Cristian Launes, Irene Martínez-de-Albeniz, María Ríos-Barnés, Maria Melé-Casas, María Hernández-García, Manuel Monsonís, Amadeu Gené, Mariona-F. de-Sevilla, Juan-José García-García, Claudia Fortuny and Victoria Fumadó
Pathogens 2024, 13(8), 622; https://doi.org/10.3390/pathogens13080622 - 26 Jul 2024
Viewed by 764
Abstract
Background: Identifying potential factors correlated with the sustained presence of antibodies in plasma may facilitate improved retrospective diagnoses and aid in the appraisal of pertinent vaccination strategies for various demographic groups. The main objective was to describe the persistence of anti-spike IgG one [...] Read more.
Background: Identifying potential factors correlated with the sustained presence of antibodies in plasma may facilitate improved retrospective diagnoses and aid in the appraisal of pertinent vaccination strategies for various demographic groups. The main objective was to describe the persistence of anti-spike IgG one year after diagnosis in children and analyse its levels in relation to epidemiological and clinical variables. Methods: A prospective, longitudinal, observational study was conducted in a university reference hospital in the Metropolitan Region of Barcelona (Spain) (March 2020–May 2021). This study included patients under 18 years of age with SARS-CoV-2 infection (positive PCR or antigen tests for SARS-CoV-2). Clinical and serological follow-up one year after infection was performed. Results: We included 102 patients with a median age of 8.8 years. Anti-spike IgG was positive in 98/102 (96%) 12 months after the infection. There were higher anti-spike IgG levels were noted in patients younger than 2 years (p = 0.034) and those with pneumonia (p < 0.001). A positive and significant correlation was observed between C-reactive protein at diagnosis and anti-spike IgG titre one-year after diagnosis (p = 0.027). Conclusion: Anti-SARS-CoV-2 IgG antibodies were detected in almost all paediatric patients one year after infection. We also observed a positive correlation between virus-specific IgG antibody titres with SARS-CoV-2 clinical phenotype (pneumonia) and age (under 2 years old). Full article
(This article belongs to the Special Issue Immune Responses to Pulmonary Pathogens)
Show Figures

Figure 1

Back to TopTop