Recent Update of Gastroretentive and Intestinal Drug Delivery Systems

A special issue of Pharmaceuticals (ISSN 1424-8247). This special issue belongs to the section "Pharmaceutical Technology".

Deadline for manuscript submissions: 30 December 2024 | Viewed by 565

Special Issue Editors


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Guest Editor
Engineering: Pharmacokinetics and Pharmaceutical Technology Area, Miguel Hernandez University, 03550 San Juan de Alicante, Spain
Interests: pharmacodynamics; ADME; bioavailability; bioequivalence studies; cell culture; WinNonlin; NONMEM; P-Glycoprotein; pharmacokinetics; drugs; BCS classification; pharmacology; pharmacokinetic modeling; formulation development of pharmaceuticals; in vitro cell culture; pharmacy; surfactants; in vivo predictive dissolution; clinical pharmacokinetics; biopharmaceutics

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Guest Editor
1. Department of Pharmaceutics and Food Technology, Faculty of Pharmacy, Complutense University, Plaza Ramón y Cajal s/n, 28040 Madrid, Spain
2. Instituto Universitario de Farmacia Industrial, Complutense University, Plaza Ramón y Cajal s/n, 28040 Madrid, Spain
Interests: drug formulation; pharmaceutical development; pharmaceutics and pharmaceutical technology; hydrogels; solid dispersions; controlled drug delivery; immediate and sustained oral release; colonic administration; topical and transdermal delivery; biopharmaceutics; analytical chemistry; pharmacology; pharmaceutics

E-Mail Website
Guest Editor
1. Department of Pharmaceutics and Food Technology, Faculty of Pharmacy, Complutense University, Plaza Ramón y Cajal s/n, 28040 Madrid, Spain
2. Instituto Universitario de Farmacia Industrial, Complutense University, Plaza Ramón y Cajal s/n, 28040 Madrid, Spain
Interests: drug formulation; pharmaceutical development; formulation development of pharmaceuticals; pharmaceutics and pharmaceutical technology; controlled drug delivery; drug formulation development; bioequivalence studies; formulations; biopharmaceutics; analytical chemistry; pharmacology; tablets; pharmaceutics

Special Issue Information

Dear Colleagues,

The journal Pharmaceuticals is planning to publish a Special Issue entitled “Recent Update of Gastroretentive and Intestinal Drug Delivery Systems”, and we are cordially inviting you to contribute with communications, research articles or high-quality review papers in this volume.

Gastroretentive and intestinal drug delivery systems have received significant attention in recent years due to their potential to improve drug efficacy and patient compliance. These technologies have the potential to revolutionize drug delivery and provide new treatment options for a variety of diseases. Different gastroretentive drug delivery systems are designed to prolong gastric retention and drug release times, and improve drug absorption, while intestinal drug delivery systems aim to target the drug to a specific site of absorption in the small or large intestine.

Recent upgrades in gastroretentive drug delivery systems include the development of various technologies such as floating drug delivery systems, mucoadhesive systems, and expandable systems. These technologies have been shown to improve drug bioavailability and reduce variability in drug release.

In the case of intestinal drug delivery systems, recent revises include the use of pH-sensitive and enzyme-sensitive polymers to enhance drug release at specific sites in the small intestine. Additionally, some of these systems have been focus on the development of colon-targeted drug delivery systems for the treatment of diseases such as ulcerative colitis and Crohn's disease.

This Special Issue intends to host research and review papers on the development of novel gastroretentive and intestinal drug delivery systems in the scientific areas of pharmaceutical technology, chemistry, biotechnology, and biomedicine. Areas of interest include, but are not limited to, drug/excipient interactions, multiparticulate systems, single-unit systems, floating, swelling, mucoadhesive, high-density, enteric-coated, controlled-release, targeted-release and biodegradable systems, biological in vitro/ex vivo/in vivo evaluation of gastroretentive and intestinal formulations and dosage forms/cell interactions.

Prof. Dr. Marival Bermejo
Dr. Paloma Marina De la Torre-Iglesias
Dr. Covadonga Álvarez-Álvarez
Guest Editors

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Pharmaceuticals is an international peer-reviewed open access monthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2900 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • drug formulation
  • controlled release systems
  • colon-targeted release systems
  • biodegradable systems
  • gastroretentive drug delivery systems
  • intestinal drug delivery systems
  • chemical–physical characterization
  • in vitro/ex vivo/in vivo evaluation
  • drug gastroretention
  • pharmaceutical development

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