Novel Candidates for the Drug Treatment of Alzheimer’s Disease

A special issue of Pharmaceuticals (ISSN 1424-8247). This special issue belongs to the section "Medicinal Chemistry".

Deadline for manuscript submissions: closed (30 November 2023) | Viewed by 858

Special Issue Editors


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Guest Editor
Interventional Radiology, Memorial Sloan Kettering Cancer Center, New York, NY, USA
Interests: Functional genomics and drug designing

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Guest Editor

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Guest Editor
Department of Biochemistry, University of Allahabad, Allahabad, India
Interests: molecular toxicology; drug design and development

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Guest Editor
Scientist, Department of Neurology, All India Institute of Medical Sciences, New Delhi, India
Interests: neurodegenerative disroders; non-coding RNAs; protein kinases

Special Issue Information

Dear Colleagues,

Alzheimer’s disease (AD) is irreversible and the most common neurodegenerative disease worldwide, which is identified by senile dementia, characterized by progressive memory and neuronal loss, combined with cognitive impairment. There is no permanent cure available for AD. The primary aim of most of the therapeutic strategies for AD is to improve the quality of daily life of the patients, especially targeting their memory, eenhancing their independence. These therapeutics work either by easing the symptoms or by slowing down the progression of the disease. Not all patients respond to the drugs in a similar manner and often, they do not respond to the drugs at all. In such cases, inventing new therapeutic molecules as well as drug repurposing become crucial to treat such patients. In order to identify and evaluate new treatments for AD, it will be critical to utilise more rigorous, evidence-based approaches of drug development and clinical trials, ensuring the mechanisms of action are confirmed, and trial designs are optimised. Hence, in line with the latest developments in therapeutic research on AD, we invite research, review and correspondence articles on novel approaches/molecules/therapeutic strategies for the treatment of Alzheimer’s disease.

Dr. Himanshu Narayan Singh
Prof. Dr. Maria de Lourdes Pereira
Prof. Dr. Bechan Sharma
Dr. Vishnu Swarup
Guest Editors

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Keywords

  • Alzheimer’s disease
  • immunotherapy
  • drug delivery
  • amyloid beta
  • cholinesterase inhibitors
  • novel therapeutics

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