Novel Therapeutic Approaches for Chronic Urticaria: Advances and Challenges

A special issue of Pharmaceuticals (ISSN 1424-8247). This special issue belongs to the section "Pharmacology".

Deadline for manuscript submissions: 28 February 2025 | Viewed by 65

Special Issue Editor


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Guest Editor
Division of Allergy, Clinical Immunology and Rheumatology, Department of Pediatrics, Federal University of São Paulo, São Paulo 01308-000, Brazil
Interests: chronic urticaria; angioedema; mast cells

Special Issue Information

Dear Colleagues,

Chronic urticaria (CU) is a prevalent and challenging condition characterized by recurring hives and/or angioedema, significantly affecting patients’ quality of life. While progress in understanding CU has led to new therapies, many patients remain unresponsive to standard treatments, underscoring the need for novel approaches.

Recent advances include the development of biologics targeting specific immune pathways, such as anti-IgE and anti-cytokine therapies, which have shown promise in improving treatment outcomes. Additionally, new small molecules and innovative formulations are being explored to enhance efficacy and safety. Personalized medicine, focusing on biomarkers and genetic profiles, is also emerging as a potential game-changer in tailoring treatments to individual patients.

However, challenges persist, including optimizing long-term safety, managing costs, and addressing treatment resistance. In this context, there is growing interest in drug repurposing and combination therapies to enhance therapeutic outcomes and address unmet clinical needs in CU.

This Special Issue invites original research and review articles on the latest therapeutic advancements in CU, including novel biologics, small molecules, personalized treatment strategies, and drug repurposing. Our goal is to highlight cutting-edge developments and explore future directions that will improve CU management and enhance patient care.

Dr. Luis Felipe Ensina
Guest Editor

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Keywords

  • chronic urticaria
  • current management
  • biosimilar pharmaceuticals
  • biologic drugs
  • monoclonal antibodies
  • tyrosine kinase inhibitors

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Published Papers

This special issue is now open for submission.
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