Free or Nanoformulated Forms of Novel Protease Inhibitors for Cancer Therapy
A special issue of Pharmaceutics (ISSN 1999-4923). This special issue belongs to the section "Nanomedicine and Nanotechnology".
Deadline for manuscript submissions: closed (20 January 2024) | Viewed by 2885
Special Issue Editor
Interests: ER stress; apoptosis; autophagy; proteasome inhibition; liver cancer; cell culture; biochemistry; proteomics
Special Issues, Collections and Topics in MDPI journals
Special Issue Information
Dear Colleagues,
I recently accepted the invitation to serve as Guest Editor for a new Special Issue of the journal Pharmaceutics on the subject of “Free or Nanoformulated Forms of Novel Protease Inhibitors for Cancer Therapy”. Many studies indicate that intracellular proteases often participate in tumor growth and progression, being involved in important biological processes such as immune and inflammatory responses, angiogenesis, proliferation, epithelial-to-mesenchymal transition (EMT) and many others. Among the anticancer strategies, the antagonization of protease activity with increasingly effective molecules is certainly an encouraging therapeutic approach, especially if formulated in nanoparticle-based delivery systems that can increase bioavailability and circulation time and allow for accumulation—specifically in tumor tissues.
This Special Issue aims to establish a collection of papers to provide cutting-edge insight into all interested in this area of research. We welcome papers in the form of full research papers or focused reviews on some aspects of the theme. If you are interested in contributing or have any questions, please do not hesitate to let us know or contact the Assistant Editor.
I look forward to receiving your contributions.
Dr. Maria Francesca Armentano
Guest Editor
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Keywords
- human proteases
- proteases inhibitors
- cancer treatment
- ubiquitin–proteasome pathway inhibitors
- apoptosis
- nanoscale drug-delivery systems
- lipidic nanoparticles
- targeting approaches
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