Topical Delivery Illuminated: Penetration Monitoring for New Age Medicines
A special issue of Pharmaceutics (ISSN 1999-4923). This special issue belongs to the section "Drug Delivery and Controlled Release".
Deadline for manuscript submissions: closed (31 March 2024) | Viewed by 5603
Special Issue Editor
Interests: semi-solid dosage forms; topical delivery; confocal Raman spectroscopy
Special Issues, Collections and Topics in MDPI journals
Special Issue Information
Dear Colleagues,
To treat diseases of the skin, eye or mucosal tissues, the topical application of dosage forms is still the most common approach. The formulations are expected to deliver an effective amount of drug to the tissue. To investigate the effectiveness of topical delivery during the development of topical dosage forms, methods such as the incubation of excised skin in Franz diffusion cells and the subsequent sampling of the receptor medium and/or the skin layers are very often performed. These lack spatial and temporal resolution and are laborious. Thus, spectroscopic methods are increasingly being used. They provide, e.g., better spatial resolution, offer time resolved measurements, allow for imaging in two or three dimensions, and/or are less laborious.
This Special Issue aims to provide an overview of the current state-of-the-art research on the use of spectroscopic, vibrational and imaging techniques in the development of topical dosage forms.
In this Special Issue, we welcome reviews and original articles that explore the use of advanced spectroscopic methods for the investigation of topical delivery and in the development of topical dosage forms. This includes, but is not limited to, spectroscopic techniques such as confocal Raman spectroscopy, Fourier-transform infrared spectroscopy, line-field confocal optical coherence tomography and soft X-ray spectroscopy. In this context, topical delivery does not only refer to the skin, but also to other tissues, such as in ophthalmic, nasal, vaginal or rectal delivery. I look forward to receiving your contributions.
Prof. Dr. Dominique Lunter
Guest Editor
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Keywords
- topical dosage form
- skin
- spectroscopy
- imaging
- penetration
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