New Insights in Nanoparticle-Based Psoriasis and Psoriatic Arthritis Therapy
A special issue of Pharmaceutics (ISSN 1999-4923). This special issue belongs to the section "Nanomedicine and Nanotechnology".
Deadline for manuscript submissions: 31 July 2025 | Viewed by 23
Special Issue Editor
Interests: targeted therapy; biologic therapy; immunology; dermatology; surgery; skin cancer; psoriasis; atopic dermatitis; bullous diseases; chronic wounds
Special Issues, Collections and Topics in MDPI journals
Special Issue Information
Dear Colleagues,
The therapeutic armamentarium for psoriasis and psoriatic arthritis has increased tremendously over the past few decades. A myriad of therapeutic alternatives are readily available for all forms of the disease. However, as part of the constant effort to enhance the precision, efficacy, and safety of current treatments and to develop novel, innovative therapeutic agents, nanoparticle-based therapies represent a particularly attractive research avenue. Modern engineering enables the delivery of nanoparticle-based drugs specifically to targeted tissues, minimizing side effects while ensuring superior transcutaneous drug penetration, allowing for a sustained and controlled drug release and thus improving efficacy and compliance. This is especially beneficial in psoriasis, given the reduced penetration of active therapeutic agents through the thick cutaneous plaques and the necessity for long-term treatment.
Numerous types of nanoparticles have been developed, each presenting unique appealing features that aim to overcome the deficiencies of conventional drugs. Thus, the solubility and penetrability of hydrophobic drugs are increased with the use of lipid-based nanoparticles, whereas sustained drug release is conferred by polymeric nanoparticles. Metal-based nanoparticles possess anti-inflammatory and antimicrobial properties and nanogels improve local hydration. Nanoparticles may be used to enhance the effects of a variety of active molecules, from natural compounds to conventional drugs and biologic agents. Moreover, new research into theranostic nanoparticles shows that they aid in the diagnosis and monitoring of therapeutic responses.
Our aim is to bring together and support both clinicians and researchers to share their experience with nanoparticle-based therapies for psoriasis and psoriatic arthritis and the results of their innovative studies in this particularly dynamic field. Therefore, we hope you find the topic of our Special Issue interesting and we warmly invite you to submit an original article or review.
We look forward to receiving your contributions.
Dr. Liliana Gabriela Popa
Guest Editor
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Keywords
- nanoparticle-based therapy
- psoriasis
- psoriasis arthritis
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