Drug Targeting and Delivery Systems for Breast Cancer Treatment
A special issue of Pharmaceutics (ISSN 1999-4923). This special issue belongs to the section "Drug Delivery and Controlled Release".
Deadline for manuscript submissions: closed (31 August 2024) | Viewed by 361
Special Issue Editors
Interests: inositol in endocrine control and carcinogenesis; tumor reversion through epigenetic and microenvironment modification; biophysical control of morphogenesis and differentiation
Special Issues, Collections and Topics in MDPI journals
Special Issue Information
Dear Colleagues,
Breast cancer is one of the most common tumors in women, and is also one of the leading causes of death. The pathogenesis recognizes a multifactorial pattern, and thus acts differently during the specific stages through which cancer progresses: local development, lymph node metastasis, and the spread over tissues and distal organs (bones, lungs, lenses, and brain). Early diagnosis is critical, since an aggressive neoplastic form is observed in 10-15% of patients, triggering metastasis development within 3 or 10 years.
From a clinical point of view, breast cancer is a fibrotic tumor that is strongly influenced, in terms of its growth and therapeutic response, by interactions with highly heterogenic stromal cell subsets and extracellular matrix components. On the other hand, recent advances in cellular and molecular profiling have dramatically increased our knowledge of cancer biology and opened up a variety of novel approaches that may defeat heterogeneous diseases in precision medicine. Breast cancer heterogeneity implies the need for personalized therapeutic approaches in order to fully characterize and investigate its pathogenetic profile; this is so that novel diagnostic tools, targeted therapies, and drug delivery systems can be developed.
The scope of this Special Issue is to provide knowledge on recent advances through a series of high-quality, multidisciplinary research articles that describe all aspects of new therapeutic strategies in the field of breast cancer treatment. Potential topics include, but are not limited to, the following: the characterization of the tumor microenvironment, targeting of novel biomarkers or cell subsets, drug repurposing, the basis of therapeutic resistance, target therapy, and drug delivery systems for breast cancer treatment. We welcome original research and review articles.
Dr. Mariano Bizzarri
Dr. Mirko Minini
Guest Editors
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Keywords
- drug delivery
- breast cancer
- target therapy
- nanoparticles
- liposomes
- microfluidics
- organoids
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