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Pharmaceutics
Special Issues
Micro/Nano Drug Delivery Systems
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Micro/Nano Drug Delivery Systems

A special issue of Pharmaceutics (ISSN 1999-4923). This special issue belongs to the section "Drug Delivery and Controlled Release".

Deadline for manuscript submissions: closed (30 September 2024) | Viewed by 3859

Special Issue Editors

Dr. Sevki Cesmeci

E-Mail Website
Guest Editor
Department of Mechanical Engineering, Georgia Southern University, Statesboro, GA 30460, USA
Interests: smart materials and structures; drug delivery systems; smart wearable technologies
Dr. Anna Angela Barba

E-Mail Website
Guest Editor
Department of Pharmacy, University of Salerno, Via Giovanni Paolo II 132, 84084 Fisciano, Italy
Interests: drug delivery systems; sustainable process; process intensification; micro/nano fabrication techniques; liposomes production; hydrogels
Special Issues, Collections and Topics in MDPI journals

Special Issue Information

Dear Colleagues,

We are happy to announce a Special Issue regarding micro/nano drug delivery systems. This issue aims to explore the recent advances, challenges, and future directions in the field of micro/nano drug delivery systems. Topics of interest include, but are not limited to, the following:

  • Micro/nano-fluidic devices for drug delivery;
  • Micro/nano fabrication techniques for drug delivery systems, including but not limited to additive manufacturing;
  • Micro/nano monitoring systems for drug delivery systems;
  • Micro/nano actuators for drug delivery control;
  • Micro/nano scale drug delivery modelling and simulation.

In this Special Issue, we welcome original research articles, review articles, and short communications regarding the applications of micro drug delivery systems in various fields, including medicine, biology, nutraceutics, cosmeceutics, fine chemistry, and engineering. Submissions will undergo a rigorous peer-review process, before being published in this Special Issue. Please ensure contributions are submitted prior to the provided deadline.

We are looking forward to receiving your contributions.

Dr. Sevki Cesmeci
Dr. Anna Angela Barba
Guest Editors

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Pharmaceutics is an international peer-reviewed open access monthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2900 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • micro/nano-fluidic devices
  • drug delivery systems
  • wearable drug delivery technologies
  • precision drug delivery
  • additive manufacturing in drug delivery systems

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Published Papers (3 papers)

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Review

20 pages, 1211 KiB  
Review
Nanotheranostics in Breast Cancer Bone Metastasis: Advanced Research Progress and Future Perspectives
by Lin Miao, Yidan Zhu, Hong Chang and Xinfeng Zhang
Pharmaceutics 2024, 16(12), 1491; https://doi.org/10.3390/pharmaceutics16121491 - 21 Nov 2024
Viewed by 360
Abstract
Breast cancer is the leading cause of cancer-related morbidity and mortality among women worldwide, with bone being the most common site of all metastatic breast cancer. Bone metastases are often associated with pain and skeletal-related events (SREs), indicating poor prognosis and poor quality [...] Read more.
Breast cancer is the leading cause of cancer-related morbidity and mortality among women worldwide, with bone being the most common site of all metastatic breast cancer. Bone metastases are often associated with pain and skeletal-related events (SREs), indicating poor prognosis and poor quality of life. Most current therapies for breast cancer bone metastasis primarily serve palliative purposes, focusing on pain management, mitigating the risk of bone-related complications, and inhibiting tumor progression. The emergence of nanodelivery systems offers novel insights and potential solutions for the diagnosis and treatment of breast cancer-related bone metastasis. This article reviews the recent advancements and innovative applications of nanodrug delivery systems in the context of breast cancer bone metastasis and explores future directions in nanotheranostics. Full article
(This article belongs to the Special Issue Micro/Nano Drug Delivery Systems)
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24 pages, 2135 KiB  
Review
Research Progress on Using Nanoparticles to Enhance the Efficacy of Drug Therapy for Chronic Mountain Sickness
by Boshen Liang, Yang Zhou, Yuliang Qin, Xinyao Li, Sitong Zhou, Kai Yuan, Rong Zhao, Xiaoman Lv and Dongdong Qin
Pharmaceutics 2024, 16(11), 1375; https://doi.org/10.3390/pharmaceutics16111375 - 26 Oct 2024
Viewed by 469
Abstract
Chronic mountain sickness (CMS) poses a significant health risk to individuals who rapidly ascend to high altitudes, potentially endangering their lives. Nanoparticles (NPs) offer an effective means of transporting and delivering drugs, protecting nucleic acids from nuclease degradation, and mediating the expression of [...] Read more.
Chronic mountain sickness (CMS) poses a significant health risk to individuals who rapidly ascend to high altitudes, potentially endangering their lives. Nanoparticles (NPs) offer an effective means of transporting and delivering drugs, protecting nucleic acids from nuclease degradation, and mediating the expression of target genes in specific cells. These NPs are almost non-toxic and easy to prepare and store, possess a large surface area, exhibit good biocompatibility and degradability, and maintain good stability. They can be utilized in the treatment of CMS to enhance the therapeutic efficacy of drugs. This paper provides an overview of the impact of NPs on CMS, discussing their roles as nanocarriers and their potential in CMS treatment. It aims to present novel therapeutic strategies for the clinical management of CMS and summarizes the relevant pathways through which NPs contribute to plateau disease treatment, providing a theoretical foundation for future clinical research. Full article
(This article belongs to the Special Issue Micro/Nano Drug Delivery Systems)
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52 pages, 12014 KiB  
Review
Advancements in Insulin Pumps: A Comprehensive Exploration of Insulin Pump Systems, Technologies, and Future Directions
by Mohammad Towhidul Islam Rimon, Md Wasif Hasan, Mohammad Fuad Hassan and Sevki Cesmeci
Pharmaceutics 2024, 16(7), 944; https://doi.org/10.3390/pharmaceutics16070944 - 15 Jul 2024
Viewed by 2382
Abstract
Insulin pumps have transformed the way diabetes is managed by providing a more accurate and individualized method of delivering insulin, in contrast to conventional injection routines. This research explores the progression of insulin pumps, following their advancement from initial ideas to advanced contemporary [...] Read more.
Insulin pumps have transformed the way diabetes is managed by providing a more accurate and individualized method of delivering insulin, in contrast to conventional injection routines. This research explores the progression of insulin pumps, following their advancement from initial ideas to advanced contemporary systems. The report proceeds to categorize insulin pumps according to their delivery systems, specifically differentiating between conventional, patch, and implantable pumps. Every category is thoroughly examined, emphasizing its unique characteristics and capabilities. A comparative examination of commercially available pumps is provided to enhance informed decision making. This section provides a thorough analysis of important specifications among various brands and models. Considered factors include basal rate and bolus dosage capabilities, reservoir size, user interface, and compatibility with other diabetes care tools, such as continuous glucose monitoring (CGM) devices and so on. This review seeks to empower healthcare professionals and patients with the essential information to improve diabetes treatment via individualized pump therapy options. It provides a complete assessment of the development, categorization, and full specification comparisons of insulin pumps. Full article
(This article belongs to the Special Issue Micro/Nano Drug Delivery Systems)
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