Topical Advisory Panel Members' Collection Series: Nanocarriers for Alternative Drug Delivery

A special issue of Pharmaceutics (ISSN 1999-4923). This special issue belongs to the section "Nanomedicine and Nanotechnology".

Deadline for manuscript submissions: 31 December 2024 | Viewed by 1467

Special Issue Editors


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Guest Editor
Faculty of Pharmacy, Institute of Pharmaceutical Technology and Regulatory Affairs, University of Szeged, Eötvös u. 6, H-6720 Szeged, Hungary
Interests: quality by design-based formulation strategies; regulatory science; patient centeredness in dosage form design; alternative administration routes; nose-to-brain delivery
Special Issues, Collections and Topics in MDPI journals

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Guest Editor
Faculty of Pharmacy, Institute of Pharmaceutical Technology and Regulatory Affairs, University of Szeged, Eötvös u. 6, H-6720 Szeged, Hungary
Interests: nose-to-brain delivery; nanomedicine; albumin nanoparticles; polymeric micelles; freeze-drying
Special Issues, Collections and Topics in MDPI journals

Special Issue Information

Dear Colleagues,

In recent years, alternative drug delivery routes have become the focus of research and development with the aim of satisfying patient expectations by applying simple and effective drug therapy avoiding invasive medication. Utilization of alternative drug delivery routes, such as nasal, pulmonary, ocular. or dermal routes, indicates several advantages (e.g., targeted therapy, bypassing biological barriers, a chance to minimize therapeutic dose, or minimization of side effects); however, from a technological point of view, it might be challenging to transport the drug to the target site. To overcome these hurdles, the variety of smart nanocarriers (e.g., lipid-, polymeric-, or protein-based systems) means an innovative approach.

The aim of this Special Issue is to describe the latest findings related to i) the development, optimization, and characterization of novel nanocarrier systems intended for alternative drug delivery, ii) the improvement of physicochemical and pharmacokinetic properties of drugs with the application of nanocarrier systems, and iii) the utilization of alternative drug delivery routes for advanced therapy.

In this Special Issue, original research articles, communication papers, and reviews are welcome.

We look forward to receiving your contributions.

Prof. Dr. Ildikó Csóka
Dr. Katona Gábor
Guest Editors

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Keywords

  • nanomedicine
  • biomaterials
  • functional nanomaterials
  • alternative administration route
  • targeted delivery
  • improved bioavailability

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Published Papers (1 paper)

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Review

17 pages, 1313 KiB  
Review
Serum Albumin in Nasal Drug Delivery Systems: Exploring the Role and Application
by Sandra Aulia Mardikasari, Gábor Katona and Ildikó Csóka
Pharmaceutics 2024, 16(10), 1322; https://doi.org/10.3390/pharmaceutics16101322 - 11 Oct 2024
Viewed by 965
Abstract
The application of serum albumin in various types of formulations has emerged as a valuable option in biomedical research, especially in the field of nasal drug delivery systems. A serum albumin-based carrier system has been employed due to several benefits, such as enhancing [...] Read more.
The application of serum albumin in various types of formulations has emerged as a valuable option in biomedical research, especially in the field of nasal drug delivery systems. A serum albumin-based carrier system has been employed due to several benefits, such as enhancing drug solubility and stability, generating the desired controlled release profile, and developing favorable properties with respect to the challenges in nasal conditions, which, in this case, involves hindering rapid elimination due to nasal mucociliary clearance. Accordingly, considering the important role of serum albumin, in-depth knowledge related to its utilization in preparing nasal drug formulation is highly encouraged. This review aimed to explore the potential application of serum albumin in fabricating nasal drug formulations and its crucial role and functionality regarding the binding interaction with nasal mucin, which significantly determines the successful administration of nasal drug formulations. Full article
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