Customized Pharmaceutics: Innovations for Diverse Populations

A special issue of Pharmaceutics (ISSN 1999-4923). This special issue belongs to the section "Physical Pharmacy and Formulation".

Deadline for manuscript submissions: 10 March 2025 | Viewed by 595

Special Issue Editors


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Guest Editor
Departamento de Produção de Matéria-Prima, Unviersidade Federal do Rio Grande do Sul, Porto Alegre 90610-000, Brazil
Interests: nanotechnology; pharmaceutical technology, skin; cosmetics; pediatric products
Special Issues, Collections and Topics in MDPI journals

E-Mail Website
Guest Editor
Departamento de Produção de Matéria-Prima, Unviersidade Federal do Rio Grande do Sul, Porto Alegre 90610-000, Brazil
Interests: nanotechnology; pharmaceutical technology, skin; cosmetics; dermatological products; topical products
Special Issues, Collections and Topics in MDPI journals

Special Issue Information

Dear Colleagues,

The field of pharmaceutics continually evolves to meet the unique needs of diverse populations, including pediatrics, geriatrics, and veterinary medicine. The demand for customized pharmaceutical solutions tailored to specific requirements is continually rising. From developing age-appropriate formulations for children to addressing the complexities of medication management in the elderly, and catering to the distinct physiological characteristics of animals, the pursuit of innovation in customized pharmaceutics remains a challenge. Advances in the field comprise, for example, nanotechnology, 3D printing and taste-masking technologies for enhanced palatability. This Special Issue aims to explore the latest developments in this dynamic field, emphasizing the importance of addressing the diverse needs of pediatric, geriatric, and veterinary patients through innovative pharmaceutical approaches.

Dr. Irene Clemes Külkamp-Guerreiro
Dr. Renata Vidor Contri
Guest Editors

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Keywords

  • nanotechnology
  • 3D printing
  • quality by design
  • patient-centric approaches
  • customized pharmaceuticals
  • pediatrics
  • geriatrics
  • veterinary medicine
  • age-appropriate formulations
  • taste masking

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Published Papers (1 paper)

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Research

17 pages, 2361 KiB  
Article
Net Promoter Score Model for Evaluating Paediatric Medicine Acceptability: Validation and Feasibility Study
by Okhee Yoo, Demi Stanford, Britta S. von Ungern-Sternberg and Lee Yong Lim
Pharmaceutics 2024, 16(12), 1513; https://doi.org/10.3390/pharmaceutics16121513 - 25 Nov 2024
Viewed by 201
Abstract
Background/Objectives: Medicine acceptability is crucial for paediatric drug development, yet its assessment remains challenging due to the multifaceted nature of sensory attributes like taste, smell, and mouthfeel. Traditional methods of acceptability evaluation often involve complex questionnaires and lack standardisation, leading to difficulties [...] Read more.
Background/Objectives: Medicine acceptability is crucial for paediatric drug development, yet its assessment remains challenging due to the multifaceted nature of sensory attributes like taste, smell, and mouthfeel. Traditional methods of acceptability evaluation often involve complex questionnaires and lack standardisation, leading to difficulties in a comparative analysis across studies. This study aimed to develop a simplified, standardised approach for assessing medicine acceptability introducing the Net Promoter Score (NPS) framework to derive a Medicine Acceptability Score (MAS). Methods: A retrospective analysis was conducted using taste assessment data from nine paediatric formulations across four studies. The MAS was calculated by identifying an optimal range for categorising participant responses, which encapsulated diverse sensory attributes into a single metric. Validation was performed across various age groups and different formulations to test the reliability and discriminatory power of MAS. Results: The MAS effectively discriminated between acceptable and unacceptable formulations, providing a practical tool for formulation development. Conclusions: The MAS offers a novel, standardised metric for evaluating paediatric medicine acceptability, addressing key limitations of traditional methods. Future studies are recommended to refine the MAS model through the establishment of benchmark scores for chronic and acute medications, thereby standardising acceptability assessment of medicines across the pharmaceutical industry. Full article
(This article belongs to the Special Issue Customized Pharmaceutics: Innovations for Diverse Populations)
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