Application Progress of Lactoferrin in Biomedicine
A special issue of Pharmaceutics (ISSN 1999-4923). This special issue belongs to the section "Biologics and Biosimilars".
Deadline for manuscript submissions: closed (30 November 2023) | Viewed by 1591
Special Issue Editors
Interests: dry eye disease; ocular surface disorders; diagnostic biomarkers; microfluidic assay; in vitro & in vivo experimental models; lactoferrin
Special Issues, Collections and Topics in MDPI journals
Special Issue Information
Dear Colleagues,
Lactoferrin (Lf), also known as lactotransferrin, is a nonheme iron-binding protein that belongs to the transferrin family. This multifunctional glycoprotein is secreted by exocrine glands and neutrophils, and has been reported to have antiviral, antibacterial, and antitumoral properties, as well as an immunomodulatory role. It is present in several different body fluids, including tears, saliva, milk, and mucosal secretions. Recent studies suggest that alterations of Lf concentration, conformation, and activity represent good biomarker candidates for the diagnosis of different diseases, such as inflammatory bowel disease, Alzheimer’s disease, and dry eye disease.
The present Special Issue aims to provide some of the latest most significant applications in the biomedical field of this protein.
The topics of interest include, but are not limited to, the physicochemical characterization of Lf, in relation to its application against oxidative stress, inflammation, cancer, and viral and bacterial infections. The development of detection methods for rapid and accurate characterization of Lf should be considered.
Both original research papers and review articles on Lf are welcome.
Dr. Piera Versura
Dr. Erika Ponzini
Guest Editors
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Keywords
- lactoferrin
- bacterial activity
- viral activity
- iron binding
- iron homeostasis
- immunomodulation
- antiviral activity
- antibacterial activity
- antioxidant activity
- antitumoral property
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