Development of New Drug Delivery Systems: Behavior Physiological Environment
A special issue of Pharmaceutics (ISSN 1999-4923). This special issue belongs to the section "Drug Delivery and Controlled Release".
Deadline for manuscript submissions: closed (30 October 2022) | Viewed by 5925
Special Issue Editor
Special Issue Information
Dear Colleagues,
The development of new and effective drug delivery systems will depend on our ability to fully understand their behaviour once administered to patients. Depending on the route of administration, drug carriers will encounter many structures and environments that can differ widely. Although there is a broad understanding of how composition and surface properties can affect pharmacokinetics and distribution, a lot remains to be uncovered about the performance of these systems in various physiological environments, in health and disease, looking at the whole body or down to single-cell level. There is also a need to reassess how drug delivery systems are characterised in the early stages of development to ensure the conditions used reflect the physiological environment as closely as possible.
This Special Issue invites studies and reviews on all aspects related to the investigation of the behaviour of new delivery systems in physiological environments, from how disease can affect the performance of delivery systems through to interaction with cells and intracellular trafficking and suggesting new methodologies for a more thorough assessment of newly developed drug carriers.
Dr. Marie-Christine Jones
Guest Editor
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Keywords
- drug delivery and targeting
- particokinetics and distribution
- cell–carrier interaction
- protein interaction
- tumour environment
- modelling
- nanotoxicity
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