Polymer Hydrogels: Synthesis, Properties and Applications

A special issue of Polymers (ISSN 2073-4360). This special issue belongs to the section "Polymer Networks".

Deadline for manuscript submissions: 10 March 2025 | Viewed by 612

Special Issue Editors


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Guest Editor
Institute of General and Physical Chemistry, University of Belgrade,Studentski trg 12/V, 11158 Belgrade, Serbia
Interests: polymers; composites; hydrogels; smart materils; synthesis; kinetics; physico-chemical processes
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Guest Editor
Innovation Center of Faculty of Technology and Metallurgy, The University of Belgrade, 4 Karnegijeva Street, 11000 Belgrade, Serbia
Interests: hydrogel; polymer; composite; swelling kinetics; adsorption; drug dellivery; tissue engineeering
Special Issues, Collections and Topics in MDPI journals

Special Issue Information

Dear Colleagues,

Hydrogels present a relatively novel class of so-called smart materials, which have attract significant attention in many fields; thus, we are pleased to announce the Special Issue “Polymer Hydrogels: Synthesis, Properties and Applications”.

Hydrogels are 3D networks of hydrophilic polymers that absorb large amounts of water, water solutions, and biological liquids

The aim of this Special Issue is to present up-to-date valuable achievements in all aspects of polymer hydrogels. This Special Issue will cover all innovative aspects of all kinds of polymeric hydrogels, such as multi-functional and stimuli-responsive hydrogels, composite hydrogels, and hybrid hydrogels.

Papers providing new hydrogel applications, studies of hydrogel behavior, and mathematical modeling of characteristic processes are preferable. Versatile methods and procedures used in hydrogel synthesis and characterization, including under conventional conditions (heating) and external fields (gamma-irradiation, microwaves, ultrasonic, etc.), are also wellcomed.  

We hope that this topic will attract a wide readership and become a valuable resource for scientists working toward the further development of hydrogels. It is our pleasure to invite you to take part in this Special Issue and submit your work (full papers and reviews). 

Prof. Dr. Jelena Jovanović
Dr. Vesna V. Panić
Guest Editors

Manuscript Submission Information

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Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Polymers is an international peer-reviewed open access semimonthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2700 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • hydrogels
  • synthesis
  • swelling
  • stimuli-responsive

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Published Papers (1 paper)

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Research

31 pages, 8437 KiB  
Article
Multifunctional Ag-Poly(N-isopropylacrylamide/itaconic Acid) Hydrogel Nanocomposites Prepared by Gamma Irradiation for Potential Application as Topical Treatment Dressings
by Jelena Spasojević, Milica Milošević, Sašenka Vidičević-Novaković, Jelena Tasić, Petar Milovanović, Marija Djurić, Dragan Ranković, Zorica Kačarević-Popović and Aleksandra Radosavljević
Polymers 2024, 16(22), 3211; https://doi.org/10.3390/polym16223211 - 19 Nov 2024
Viewed by 302
Abstract
Today, hydrogel dressings that can protect injury sites and effectively promote healing have become highly desirable in wound management. Therefore, multifunctional silver-poli(N-isopropylacrylamide/itaconic acid) (Ag-P(NiPAAm/IA)) hydrogel nanocomposites were developed for potential application as topical treatment dressings. The radiolytic method, used for the [...] Read more.
Today, hydrogel dressings that can protect injury sites and effectively promote healing have become highly desirable in wound management. Therefore, multifunctional silver-poli(N-isopropylacrylamide/itaconic acid) (Ag-P(NiPAAm/IA)) hydrogel nanocomposites were developed for potential application as topical treatment dressings. The radiolytic method, used for the crosslinking of the polymer matrix as well as for the in situ incorporation of silver nanoparticles (AgNPs) into the polymer matrix, enables the preparation of hydrogel nanocomposites without introducing harmful and toxic agents. Moreover, materials produced using γ-irradiation are simultaneously sterilized, thus fulfilling one of the basic requirements regarding their potential biomedical applications. The NiPAAm/IA ratio and the presence of AgNPs influenced the microstructural parameters of the investigated systems. Increasing the IA content leads to the formation of a more porous polymer matrix with larger pores, while the incorporated AgNPs act as additional junction points, decreasing the porosity and pore size of the resulting nanocomposite hydrogels. Swelling studies showed that most investigated systems uptake the fluids from their surroundings by non-Fick diffusion. Further, the Ag+ ion release, antibacterial activity, and cytotoxicity of Ag-P(NiPAAm/IA) hydrogel nanocomposites were examined to evaluate their biomedical potential. All hydrogel nanocomposites showed an initial burst release of Ag+ ions (useful in preventing bacteria adherence and biofilm formation), followed by a slower release of the same (ensuring sterility for longer use). An antibacterial activity test against Escherichia coli and Staphylococcus aureus showed that Ag-P(NiPAAm/IA) hydrogel nanocomposites, with silver concentrations around 10 ± 1 ppm, successfully prevent bacterial growth. Finally, it was shown that the investigated hydrogel nanocomposites do not exhibit a cytotoxic effect on human keratinocyte HaCaT cells. Therefore, these multifunctional hydrogel nanocomposites may promote wound repair and show promising potential for application as functional wound dressing. Full article
(This article belongs to the Special Issue Polymer Hydrogels: Synthesis, Properties and Applications)
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