Small Molecule Organic Compounds: Synthesis and Medicinal Properties
A special issue of Processes (ISSN 2227-9717). This special issue belongs to the section "Chemical Processes and Systems".
Deadline for manuscript submissions: 20 March 2025 | Viewed by 737
Special Issue Editor
Special Issue Information
Dear Colleagues,
Small molecule drugs are synthetic medicinal chemical entities designed to mimic, enhance, or reduce the behavior of natural substances within the body. The structures of small molecule organic compounds can be designed to interact particularly with specific pharmacological targets. By modifying the atomic composition, their properties can be tuned to a specific purpose, obtaining only the anticipated response. The flexibility offered by exploring all chemical space in this way offers small molecule approaches a marked advantage over the modalities. Most marketed drugs are small molecules with low molecular weight and were designed and developed to prompt a specific biological process in the body. Examples include antibiotics (Penicillin), analgesics (Paracetamol), and synthetic hormones (Corticosteroids). On average, it takes 10-15 years to develop a new medicine from initial discovery to regulatory approval, and the cost is often in the billions. The discovery of new drugs remains a significant challenge, involving teams of researchers from chemistry, biology, drug development, science, and informatics.
This Special Issue on ’’Small Molecule Organic Compounds: Synthesis and Medicinal Properties’’ focuses on recent advances in synthesizing novel biologically active small molecule organic compounds. Topics include, but are not limited to, methods and/or applications in the following areas:
- Design and synthesis of novel bioactive small molecule organic compounds;
- Multi-step synthesis and medicinal chemistry;
- Biological evaluation of organic molecules for specific targets with molecular docking studies;
- Nitrogen-containing bio-active heterocycles with SAR studies.
Dr. Srinivasulu Cherukupalli
Guest Editor
Manuscript Submission Information
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Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Processes is an international peer-reviewed open access monthly journal published by MDPI.
Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2400 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.
Keywords
- organic synthesis
- heterocyclic compounds
- medicinal chemistry
- molecular docking
- biological evaluation
- SAR studies
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