Case Reports in Obstetrics and Gynecology

A special issue of Reports (ISSN 2571-841X). This special issue belongs to the section "Obstetrics/Gynaecology".

Deadline for manuscript submissions: 30 November 2024 | Viewed by 2059

Special Issue Editor


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Guest Editor
Department of Obstetrics and Gynecology, “Carol Davila” University of Medicine and Pharmacy, 020021 Bucharest, Romania
Interests: gynecology; gynecologic oncology; laparoscopy; endometriosis and fertility preservation in women with cancer
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Special Issue Information

Dear Colleagues,

Rare case reports in obstetrics and gynecology play a crucial role in expanding our understanding of unique and atypical clinical situations. These reports provide valuable insights into uncommon presentations, unexpected complications, and novel diagnosis and treatment approaches. By sharing these rare cases, healthcare professionals can enhance their diagnostic and management skills, ultimately improving patient care. Furthermore, the documentation of such cases contributes to the collective knowledge in obstetrics and gynecology, fostering ongoing learning and potentially guiding future research.

For this Special Issue, we welcome interesting rare case reports/interesting images in the fields of different maternal and fetal pathologies, gynecologic oncology, and new imaging methods in obstetrics and gynecology.

Dr. Nicolae Gica
Guest Editor

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Keywords

  • obstetrics
  • gynecology
  • maternal and fetal
  • diagnosis and treatment

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Published Papers (2 papers)

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9 pages, 10293 KiB  
Case Report
A Case Report of the Synchronous Occurrence of Ovarian Granulosa Cell Tumour and Malignant Endometrial Polyp with Immunohistochemical Expression of Hormone Receptors and Biomarkers p-53 and Ki-67
by Krum Vladov, Ekaterina Uchikova, Maria Koleva-Ivanova, Kamen Yamakov, Veselin Belovezhdov, Gita Yamakova-Vladova and Eleonora Hristova-Atanasova
Reports 2024, 7(4), 103; https://doi.org/10.3390/reports7040103 - 20 Nov 2024
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Abstract
Background and Clinical Significance: Abnormal uterine bleeding during the postmenopausal years is a pathological sign that may be due to simultaneous intrauterine and ovarian pathology. Granulosa cell tumours of the ovary are malignant neoplasms producing oestradiol, which leads to the abnormal proliferation of [...] Read more.
Background and Clinical Significance: Abnormal uterine bleeding during the postmenopausal years is a pathological sign that may be due to simultaneous intrauterine and ovarian pathology. Granulosa cell tumours of the ovary are malignant neoplasms producing oestradiol, which leads to the abnormal proliferation of the endometrium, precancerous lesions, and endometrial carcinoma type I. Case Presentation: The authors present a clinical case of a 67-year-old woman with postmenopausal bleeding who underwent a total abdominal hysterectomy with bilateral adnexectomy, pelvic lymphadenectomy, and partial omentectomy. The histopathological examination showed a granulosa cell adult-type ovarian tumour and a malignant endometrial polyp with atypical hyperplasia of the endometrium. Conclusions: The immunohistochemical analysis of the malignant endometrial polyp confirmed the expression of oestrogen, progesterone receptors, and the biomarker Ki-67. Full article
(This article belongs to the Special Issue Case Reports in Obstetrics and Gynecology)
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5 pages, 174 KiB  
Case Report
Management of Pregnancy in a Patient with Familial Hypercholesterolemia and Previous Myocardial Infarction—Treatment with LDL Apheresis: A Case Report
by Milos Milincic, Jovana Todorovic, Stefan Dugalic, Ivana Novakovic, Maja Macura, Katarina Lalic and Miroslava Gojnic Dugalic
Reports 2024, 7(2), 39; https://doi.org/10.3390/reports7020039 - 19 May 2024
Viewed by 1032
Abstract
Familial hypercholesterolemia, a genetic disorder marked by elevated low-density lipoprotein cholesterol (LDL-C), poses significant risks for premature atherosclerosis and cardiovascular diseases, particularly during pregnancy. One of the safe methods of treating this condition in pregnancy is with the use of LDL apheresis. We [...] Read more.
Familial hypercholesterolemia, a genetic disorder marked by elevated low-density lipoprotein cholesterol (LDL-C), poses significant risks for premature atherosclerosis and cardiovascular diseases, particularly during pregnancy. One of the safe methods of treating this condition in pregnancy is with the use of LDL apheresis. We present a 38-year-old primigravida with homozygous Familial Hypercholesterolemia (HoFH), ischemic cardiomyopathy, and angina pectoris. Two years before conception, extremely elevated lipid levels prompted statin therapy and lifestyle changes. Stent placements followed acute myocardial infarction. When planning pregnancy, statins were discontinued, but lipid levels elevated. LDL apheresis was initiated, achieving a 60% reduction. Throughout pregnancy, 16 LDL apheresis sessions were performed every 14 days, maintaining optimal lipid profiles. A cesarean section was performed in the 38th week of gestation, delivering a healthy infant. The patient resumed statin therapy after 8 months of breastfeeding. The patient maintained cardiovascular health, demonstrating the feasibility of controlled HoFH pregnancies. This case highlights the successful management of HoFH during pregnancy using LDL apheresis, ensuring maternal and fetal well-being. Future research on novel treatments and their safety during pregnancy is essential for refining therapeutic approaches in similar cases. Full article
(This article belongs to the Special Issue Case Reports in Obstetrics and Gynecology)
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