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Reprod. Med.
Special Issues
Feature Papers in Celebration of the Fourth Anniversary of the...
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Feature Papers in Celebration of the Fourth Anniversary of the Founding of Reproductive Medicine

A special issue of Reproductive Medicine (ISSN 2673-3897).

Deadline for manuscript submissions: closed (31 December 2023) | Viewed by 4448

Special Issue Editor

Prof. Dr. Stefano Palomba

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Guest Editor
Unit of Gynecology, Sant’Andrea Hospital of Rome, University Sapienza of Rome, Via Grottarossa 1039, 00189 Rome, Italy
Interests: reproductive surgery; infertility; PCOS; ovulation induction
Special Issues, Collections and Topics in MDPI journals

Special Issue Information

Dear Colleagues,

This Special Issue is designed to celebrate the fourth anniversary of the founding of the open access journal Reproductive Medicine. The Special Issue covers all topics related to reproductive medicine. Research fields of interest include (but are not limited to) reproductive surgery, female and male infertility, PCOS, endocrine diseases influencing reproduction, ovulation induction, ovarian stimulation for IVF/ICSI cycles, etc. Distinguished researchers worldwide will be invited to contribute to this Special Issue. Potential contributors/invited authors are kindly requested to submit a tentative title and a short abstract to our Editorial Office ([email protected]) for pre-evaluation. Please note that selected full papers will still be subjected to a thorough and rigorous peer review. All papers will be published on an ongoing basis. Papers will be published with full open access after peer review.

Prof. Dr. Stefano Palomba
Guest Editor

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Reproductive Medicine is an international peer-reviewed open access quarterly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 1000 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • reproductive medicine
  • reproductive surgery
  • female and male infertility
  • PCOS
  • endocrine diseases influencing reproduction
  • ovulation induction
  • ovarian stimulation for IVF/ICSI cycles

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Further information on MDPI's Special Issue polices can be found here.

Published Papers (2 papers)

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12 pages, 267 KiB  
Article
Relationship between Ovarian Reserve Markers and Body Mass Index in Infertile Women with and without Polycystic Ovary Syndrome: A Retrospective Case–Control Study
by Luisa Casadei, Ilaria Nacci, Veronica Vicomandi, Roberto Pietro Sorge and Carlo Ticconi
Reprod. Med. 2023, 4(3), 198-209; https://doi.org/10.3390/reprodmed4030018 - 17 Aug 2023
Cited by 1 | Viewed by 2207
Abstract
This study, carried out on 94 women with polycystic ovary syndrome (PCOS) and 176 controls without it, investigated the influence of body mass index (BMI) on serum levels of antimüllerian hormone (AMH), follicle stimulating hormone (FSH), luteinizing hormone (LH), and 17ß-estradiol (E2) in [...] Read more.
This study, carried out on 94 women with polycystic ovary syndrome (PCOS) and 176 controls without it, investigated the influence of body mass index (BMI) on serum levels of antimüllerian hormone (AMH), follicle stimulating hormone (FSH), luteinizing hormone (LH), and 17ß-estradiol (E2) in infertile patients. Patients were assigned to four subgroups according to age (<35 or ≥35 years) and BMI (<25 kg/m2 or ≥25 kg/m2). Significant differences between PCOS-affected and control women were observed with respect to most of the parameters of interest. In both PCOS-affected and control women, age was inversely correlated with AMH. In the control patients, age was directly correlated with FSH and LH. In women affected by PCOS, no correlation was found between BMI and serum levels of AMH, E2, and LH, except FSH. No correlation was found between BMI and markers of ovarian reserve in control women. BMI was not correlated with AMH in any of the four subgroups considered regardless of the presence of PCOS. An inverse correlation was found only in PCOS-affected women aged ≥35 years between a BMI < 25/FSH and a BMI ≥ 25/LH. The possible association between BMI and ovulation disorder (OD) was investigated in 96 control women aged ≤37 years. In women with OD, the BMI values were significantly higher and FSH and E2 levels were lower than those of patients without OD. Taken together, our data suggest that BMI is not related to hormonal parameters of ovarian reserve, irrespective of the presence of PCOS, and could influence ovulation disorder rather than cause a decrease in ovarian reserve. Full article
(This article belongs to the Special Issue Feature Papers in Celebration of the Fourth Anniversary of the Founding of Reproductive Medicine)

Other

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6 pages, 1191 KiB  
Case Report
Prenatal Evaluation of a Fetal Cystic Hygroma: An Unexpected Finding of a De Novo Fetal BRCA1 Deletion Case Report
by Stephanie C. Laniewski, LauraAnne Hirschler, Anwar M. Iqbal and Neil S. Seligman
Reprod. Med. 2023, 4(4), 242-247; https://doi.org/10.3390/reprodmed4040022 - 23 Oct 2023
Cited by 1 | Viewed by 1626
Abstract
This case presents a novel occurrence of a de novo BRCA1 gene deletion in a fetus with a cystic hygroma. Chorionic villus sampling (CVS) was performed for chromosome G-banding analysis, demonstrating a normal karyotype: 46, XX. Chromosome microarray analysis performed as a reflex [...] Read more.
This case presents a novel occurrence of a de novo BRCA1 gene deletion in a fetus with a cystic hygroma. Chorionic villus sampling (CVS) was performed for chromosome G-banding analysis, demonstrating a normal karyotype: 46, XX. Chromosome microarray analysis performed as a reflex test revealed an 80 kb deletion on 17q21.31, encompassing the BRCA1 gene. Follow-up FISH analysis performed on parental blood samples yielded negative results, confirming that the deletion was de novo in the fetus. Subsequent anatomic ultrasound evaluation showed no identifiable structural defects, and it was concluded that the microdeletion was unlikely to be the cause of the cystic hygroma. Regardless, it will be imperative that the patient’s daughter be appropriately counseled regarding the implications of carrying a BRCA1 deletion and the need for heightened surveillance in adulthood. As BRCA1 genetic testing is traditionally performed on adult patients with informed consent, this case report highlights the need for ongoing conversations and research in the management of incidental fetal diagnosis discovered during routine prenatal testing, as well as the care and counseling of these patients and their families. Full article
(This article belongs to the Special Issue Feature Papers in Celebration of the Fourth Anniversary of the Founding of Reproductive Medicine)
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