Advances in Ophthalmic Drug Delivery
A special issue of Scientia Pharmaceutica (ISSN 2218-0532).
Deadline for manuscript submissions: closed (30 April 2019) | Viewed by 584
Special Issue Editors
Interests: ocular drug delivery
Special Issues, Collections and Topics in MDPI journals
Interests: ocular drug delivery; ocular pharmacokinetic; drug development; pharmacogenetics; clinical and translational research
Special Issues, Collections and Topics in MDPI journals
Special Issue Information
Dear Colleagues,
The eye is a specialized and well-isolated organ that presents highly efficient mechanisms in order to avoid the penetration of micro-organisms and xenobiotics. These defence mechanisms and the eyeball anatomical structure cause problems of low drug bioavailability after local administration. In this situation, the ophthalmic drug delivery systems acquire great importance, because more specialized systems can promote the bioavailability and can increase the contact time. In the last years, effort has been made to develop more effective topical formulations, including eye drops, in situ gels, medicated soft contact lenses, and nanomedicine approaches, among others. In addition, a new formulation for local ocular routes of administration, such as subconjunctival, sub-tenons, retrovulvar, and intracameral or intravitreal routes, has been proposed, so as to increase the absorption in the area of the eye needing to be medicated.
In this Special Issue, our goal is to highlight papers describing the advances in ophthalmic drug delivery systems for topical and local ocular administration.
Prof. Dr. Francisco Javier Otero-Espinar
Dr. Anxo Fernandez Ferreiro
Guest Editors
Manuscript Submission Information
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Keywords
- Ophthalmic drug delivery systems
- Ocular drug administration
- Ocular routes of administration
- Ocular bioavailability
- Anterior eye segment drug administration
- Posterior eye segment drug administration
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