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Acousto-Optic Sensing for Biomedical Imaging...
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Acousto-Optic Sensing for Biomedical Imaging

A special issue of Sensors (ISSN 1424-8220). This special issue belongs to the section "Biomedical Sensors".

Deadline for manuscript submissions: closed (16 October 2020) | Viewed by 10588

Special Issue Editor

Dr. Ireneusz Grulkowski

E-Mail Website
Guest Editor
Institute of Physics, Nicolaus Copernicus University, ul. Grudziądzka 5/7, 87-100 Toruń, Poland
Interests: biomedical imaging; bio-optics; biophotonics; optical engineering; acousto-optics; biomechanics

Special Issue Information

Dear Colleagues,

Biomedical imaging is a rapidly developing field that enables visualization of structure and functions of biological objects at different levels of their organization (from the whole body to subcellular structures). Generally, an imaging system allows mapping spatial and/or temporal (dynamic) properties of an object by measuring (probing) its physical properties. Therefore, biomedical imaging integrates physics, engineering, fundamental biology, and clinical medicine. Although acousto-optics is a relatively mature field, a growing spectrum of applications of acousto-optic instrumentation demonstrates that merging acoustics (ultrasonics) and optics provides new perspectives for the development of imaging technologies.

This Special Issue aims at presenting the advances in the development and characterization of new configurations and concepts that utilize the interaction of ultrasound (acoustic wave) and light to probe or image the properties of biological systems. The issue is also open for original research articles or reviews showing state-of-the-art methods that combine acoustics and optics for applications in biomedicine. The topics covered by this issue include (but are not limited to): acousto-optic imaging, opto-acoustic (photoacoustic) imaging, acousto-optic tomography, acousto-optic sensors and scanners, acousto-optics in microscopy and endoscopy, optical probing of biomechanical properties, etc.

Dr. Ireneusz Grulkowski
Guest Editor

Manuscript Submission Information

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Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Sensors is an international peer-reviewed open access semimonthly journal published by MDPI.

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Keywords

  • Acousto-optics
  • Opto-acoustics/photoacoustics
  • Acousto-optic tomography
  • Acousto-optic devices
  • Acousto-optic sensors
  • Biomedical imaging
  • Microscopy

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Published Papers (2 papers)

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Review

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30 pages, 22598 KiB  
Review
A Review of Endogenous and Exogenous Contrast Agents Used in Photoacoustic Tomography with Different Sensing Configurations
by Victor T.C. Tsang, Xiufeng Li and Terence T.W. Wong
Sensors 2020, 20(19), 5595; https://doi.org/10.3390/s20195595 - 29 Sep 2020
Cited by 40 | Viewed by 5712
Abstract
Optical-based sensing approaches have long been an indispensable way to detect molecules in biological tissues for various biomedical research and applications. The advancement in optical microscopy is one of the main drivers for discoveries and innovations in both life science and biomedical imaging. [...] Read more.
Optical-based sensing approaches have long been an indispensable way to detect molecules in biological tissues for various biomedical research and applications. The advancement in optical microscopy is one of the main drivers for discoveries and innovations in both life science and biomedical imaging. However, the shallow imaging depth due to the use of ballistic photons fundamentally limits optical imaging approaches’ translational potential to a clinical setting. Photoacoustic (PA) tomography (PAT) is a rapidly growing hybrid imaging modality that is capable of acoustically detecting optical contrast. PAT uniquely enjoys high-resolution deep-tissue imaging owing to the utilization of diffused photons. The exploration of endogenous contrast agents and the development of exogenous contrast agents further improve the molecular specificity for PAT. PAT’s versatile design and non-invasive nature have proven its great potential as a biomedical imaging tool for a multitude of biomedical applications. In this review, representative endogenous and exogenous PA contrast agents will be introduced alongside common PAT system configurations, including the latest advances of all-optical acoustic sensing techniques. Full article
(This article belongs to the Special Issue Acousto-Optic Sensing for Biomedical Imaging )
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Other

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10 pages, 5355 KiB  
Letter
Polarizer-Free AOTF-Based SWIR Hyperspectral Imaging for Biomedical Applications
by Vladislav Batshev, Alexander Machikhin, Grigoriy Martynov, Vitold Pozhar, Sergey Boritko, Milana Sharikova, Vladimir Lomonov and Alexander Vinogradov
Sensors 2020, 20(16), 4439; https://doi.org/10.3390/s20164439 - 8 Aug 2020
Cited by 15 | Viewed by 4048
Abstract
Optical biomedical imaging in short wave infrared (SWIR) range within 0.9–1.7 μm is a rapidly developing technique. For this reason, there is an increasing interest in cost-effective and robust hardware for hyperspectral imaging data acquisition in this range. Tunable-filter-based solutions are of particular [...] Read more.
Optical biomedical imaging in short wave infrared (SWIR) range within 0.9–1.7 μm is a rapidly developing technique. For this reason, there is an increasing interest in cost-effective and robust hardware for hyperspectral imaging data acquisition in this range. Tunable-filter-based solutions are of particular interest as they provide image processing flexibility and effectiveness in terms of collected data volume. Acousto-optical tunable filters (AOTFs) provide a unique set of features necessary for high-quality SWIR hyperspectral imaging. In this paper, we discuss a polarizer-free configuration of an imaging AOTF that provides a compact and easy-to-integrate design of the whole imager. We have carried out image quality analysis of this system, assembled it and validated its efficiency through multiple experiments. The developed system can be helpful in many hyperspectral applications including biomedical analyses. Full article
(This article belongs to the Special Issue Acousto-Optic Sensing for Biomedical Imaging )
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