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Optical Nanosensors for Biosensing

A special issue of Sensors (ISSN 1424-8220). This special issue belongs to the section "Optical Sensors".

Deadline for manuscript submissions: closed (10 July 2020) | Viewed by 13719

Special Issue Editors


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Guest Editor
Institute of Nanoscience and Nanotechnology, NCSR "Demokritos", Patriarchou Grigoriou E’ and 27 Neapoleos Street, 15310 Aghia Paraskevi, Greece
Interests: optical biochemical sensors; photonic structures; metal oxide nanostructures; nanomaterials for optoelectronic and sensing devices
Special Issues, Collections and Topics in MDPI journals

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Guest Editor
Immunoassay/Immunosensors Lab, Institute of Nuclear & Radiological Sciences & Technology, Energy & Safety, NCSR “Demokritos”, 15310 Aghia Paraskevi, Greece
Interests: immunoassays and immunosensors for biological markers; environmental or food hazard; new substrates and methods for biomolecule immobilization and/or detection; development and evaluation of bioanalytical microsystems
Special Issues, Collections and Topics in MDPI journals

Special Issue Information

Dear Colleagues,

Probing matter with light has been one of the most elegant and non-destructive means for scientists to study, explore, and understand biological materials and processes. A plethora of examples exist, where light has been the enabling tool that probes, interrogates, and elucidates biochemical events either in vitro or in vivo, and has been humankind’s ally in detecting biological entities in minute quantities. The recent advances in nanofabrication and emerging nanomaterials and nanostructures have been enhancing the optical detection “arsenal” with disruptive and breakthrough nanophotonic tools, which will form the basis for the next generation of optical sensing techniques and devices.

This Special Issue is devoted to collecting the recent advances in nanofabrication, nanomaterials, and nanophotonics that contribute to the development of novel and radical optical biosensing tools applicable to medical and biochemical diagnostics (both in vivo and in vitro), environmental monitoring, food quality and safety assessment, and biohazard detection. Topics may include, but are not limited to, the following:

  • Novel nanostructures and nanomaterials for optical sensing
  • Nanofabrication techniques for optical transducers
  • Nanostructures for optical sensors—nanophotonics
  • Biodiagnostics
  • Label-free optical transducers
  • Optical cellular probes
  • Nanomaterials for intracellular imaging

Dr. Eleni Makarona
Dr. Pangiota Petrou
Guest Editors

Manuscript Submission Information

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Keywords

  • nanophotonics
  • nano-optics
  • optical sensors
  • label-free detection schemes
  • in vitro diagnostics
  • in vivo diagnostics
  • cellular and intracellular imaging
  • optical cellular probes
  • pathogen/microorganism detection

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Published Papers (2 papers)

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Research

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8 pages, 1326 KiB  
Article
High-Refractive-Index Materials for Giant Enhancement of the Transverse Magneto-Optical Kerr Effect
by Edwin Moncada-Villa and J. Ricardo Mejía-Salazar
Sensors 2020, 20(4), 952; https://doi.org/10.3390/s20040952 - 11 Feb 2020
Cited by 12 | Viewed by 3124
Abstract
The ability of plasmonic structures to confine and enhance light at nanometer length scales has been traditionally exploited to boost the magneto-optical effects in magneto-plasmonic structures. These platforms allows for light control via externally applied magnetic fields, which is of prime importance for [...] Read more.
The ability of plasmonic structures to confine and enhance light at nanometer length scales has been traditionally exploited to boost the magneto-optical effects in magneto-plasmonic structures. These platforms allows for light control via externally applied magnetic fields, which is of prime importance for sensing, data storage, optical-isolation, and telecommunications applications. However, applications are hindered by the high-level of ohmic losses associated to metallic and ferromagnetic components. Here, we use a lossless all-dielectric platform for giant enhancement of the magneto-optical effects. Our structure consists of a high-refractive index dielectric film on top of a magnetic dielectric substrate. We numerically demonstrate an extraordinarily enhanced transverse magneto-optical Kerr effect due to the Fabry–Perot resonances supported by the high-refractive index slab. Potential applications for sensing and biosensing are also illustrated in this work. Full article
(This article belongs to the Special Issue Optical Nanosensors for Biosensing)
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Review

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21 pages, 2651 KiB  
Review
Novel Surface-Enhanced Raman Spectroscopy Techniques for DNA, Protein and Drug Detection
by Chuanpin Chen, Wenfang Liu, Sanping Tian and Tingting Hong
Sensors 2019, 19(7), 1712; https://doi.org/10.3390/s19071712 - 10 Apr 2019
Cited by 70 | Viewed by 9795
Abstract
Surface-enhanced Raman spectroscopy (SERS) is a vibrational spectroscopic technique in which the Raman scattering signal strength of molecules, absorbed by rough metals or the surface of nanoparticles, experiences an exponential growth (103–106 times and even 1014–1015 times) [...] Read more.
Surface-enhanced Raman spectroscopy (SERS) is a vibrational spectroscopic technique in which the Raman scattering signal strength of molecules, absorbed by rough metals or the surface of nanoparticles, experiences an exponential growth (103–106 times and even 1014–1015 times) because of electromagnetic or chemical enhancements. Nowadays, SERS has attracted tremendous attention in the field of analytical chemistry due to its specific advantages, including high selectivity, rich informative spectral properties, nondestructive testing, and the prominent multiplexing capabilities of Raman spectroscopy. In this review, we present the applications of state-of-the-art SERS for the detection of DNA, proteins and drugs. Moreover, we focus on highlighting the merits and mechanisms of achieving enhanced SERS signals for food safety and clinical treatment. The machine learning techniques, combined with SERS detection, are also indicated herein. This review concludes with recommendations for future studies on the development of SERS. Full article
(This article belongs to the Special Issue Optical Nanosensors for Biosensing)
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