sensors-logo

Journal Browser

Journal Browser

Spintronic and Magnetic Platforms for Biosensing

A special issue of Sensors (ISSN 1424-8220). This special issue belongs to the section "Physical Sensors".

Deadline for manuscript submissions: closed (30 June 2020) | Viewed by 6480

Special Issue Editor


E-Mail Website
Guest Editor
Politecnico di Milano, via Giuseppe Colombo, 81 20133 Milano, Italy
Interests: spintronics; spin textures; spin transport; magnetization dynamics; spin waves; spin-orbit torques; electrical control of magnetization; advanced magnetic nanofabrication
Special Issues, Collections and Topics in MDPI journals

Special Issue Information

Dear Colleagues,

In recent years, magnetic platforms have gained interest as a promising reference technology in the field of biosensing, due to their high sensitivity and integrability. The use of magnetic labels for both the manipulation and detection of biological entities—such as biomolecules, pathogens, and cells—is one of the key advantages of magnetic techniques. One of the most utilized magnetic biosensing approaches is based on the use of external magnetic fields to magnetize paramagnetic or superparamagnetic particles and crystals labelling the recognition event between complementary biomolecules on the surface of a magnetic field sensor. Depending on the specific binding scheme and application, different technologies have been employed to detect the magnetic markers, including coils, magnetoresistive devices, Hall effect devices, and various optical and imaging techniques. Magnetic fields can be applied either externally or with integrated microconductors or magnetic micro and nanoconduits, allowing for miniaturization. The possibility to create gradients of magnetic fields enables the use of magnetophoresis in combination with electric or magnetic sensors, giving rise to different detection strategies. In addition, very recently, spintronic biosensors have been used to detect the weak magnetic fields arising from the activity of neurons or cardiac muscle cells in both in vitro and in vivo experiments.

This Special Issue will cover a wide range of topics, including the design, fabrication and characterization of magnetic sensing platforms, physical working principles, modeling and simulation, and new biological applications.

Prof. Daniela Petti
Guest Editor

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Sensors is an international peer-reviewed open access semimonthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2600 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • magnetic particles
  • magnetoresistive sensors
  • Hall effect sensors
  • magneto-optical sensors
  • SQUID sensors
  • NEMS- and MEMS-based magnetic sensors
  • magnetophoresis

Benefits of Publishing in a Special Issue

  • Ease of navigation: Grouping papers by topic helps scholars navigate broad scope journals more efficiently.
  • Greater discoverability: Special Issues support the reach and impact of scientific research. Articles in Special Issues are more discoverable and cited more frequently.
  • Expansion of research network: Special Issues facilitate connections among authors, fostering scientific collaborations.
  • External promotion: Articles in Special Issues are often promoted through the journal's social media, increasing their visibility.
  • e-Book format: Special Issues with more than 10 articles can be published as dedicated e-books, ensuring wide and rapid dissemination.

Further information on MDPI's Special Issue polices can be found here.

Published Papers (2 papers)

Order results
Result details
Select all
Export citation of selected articles as:

Research

Jump to: Other

18 pages, 6358 KiB  
Article
Reviewing Magnetic Particle Preparation: Exploring the Viability in Biosensing
by Daniel Kappe, Laila Bondzio, Joris Swager, Andreas Becker, Björn Büker, Inga Ennen, Christian Schröder and Andreas Hütten
Sensors 2020, 20(16), 4596; https://doi.org/10.3390/s20164596 - 16 Aug 2020
Cited by 6 | Viewed by 2781
Abstract
In this review article, we conceptually investigated the requirements of magnetic nanoparticles for their application in biosensing and related them to example systems of our thin-film portfolio. Analyzing intrinsic magnetic properties of different magnetic phases, the size range of the magnetic particles was [...] Read more.
In this review article, we conceptually investigated the requirements of magnetic nanoparticles for their application in biosensing and related them to example systems of our thin-film portfolio. Analyzing intrinsic magnetic properties of different magnetic phases, the size range of the magnetic particles was determined, which is of potential interest for biosensor technology. Different e-beam lithography strategies are utilized to identify possible ways to realize small magnetic particles targeting this size range. Three different particle systems from 500 μm to 50 nm are produced for this purpose, aiming at tunable, vertically magnetized synthetic antiferromagnets, martensitic transformation in a single elliptical, disc-shaped Heusler Ni50Mn32.5Ga17.5 particle and nanocylinders of Co2MnSi-Heusler compound. Perspectively, new applications for these particle systems in combination with microfluidics are addressed. Using the concept of a magnetic on–off ratchet, the most suitable particle system of these three materials is validated with respect to magnetically-driven transport in a microfluidic channel. In addition, options are also discussed for improving the magnetic ratchet for larger particles. Full article
(This article belongs to the Special Issue Spintronic and Magnetic Platforms for Biosensing)
Show Figures

Figure 1

Other

Jump to: Research

12 pages, 921 KiB  
Letter
On-Chip Selective Capture and Detection of Magnetic Fingerprints of Malaria
by Francesca Milesi, Marco Giacometti, Lorenzo Pietro Coppadoro, Giorgio Ferrari, Gianfranco Beniamino Fiore and Riccardo Bertacco
Sensors 2020, 20(17), 4972; https://doi.org/10.3390/s20174972 - 2 Sep 2020
Cited by 8 | Viewed by 2970
Abstract
The development of innovative diagnostic tests is fundamental in the route towards malaria eradication. Here, we discuss the sorting capabilities of an innovative test for malaria which allows the quantitative and rapid detection of all malaria species. The physical concept of the test [...] Read more.
The development of innovative diagnostic tests is fundamental in the route towards malaria eradication. Here, we discuss the sorting capabilities of an innovative test for malaria which allows the quantitative and rapid detection of all malaria species. The physical concept of the test exploits the paramagnetic property of infected erythrocytes and hemozoin crystals, the magnetic fingerprints of malaria common to all species, which allows them to undergo a selective magnetophoretic separation driven by a magnetic field gradient in competition with gravity. Upon separation, corpuscles concentrate at the surface of a silicon microchip where interdigitated electrodes are placed in close proximity to magnetic concentrators. The impedance variation proportional to the amount of attracted particles is then measured. The capability of our test to perform the selective detection of infected erythrocytes and hemozoin crystals has been tested by means of capture experiments on treated bovine red blood cells, mimicking the behavior of malaria-infected ones, and suspensions of synthetic hemozoin crystals. Different configuration angles of the chip with respect to gravity force and different thicknesses of the microfluidic chamber containing the blood sample have been investigated experimentally and by multiphysics simulations. In the paper, we describe the optimum conditions leading to maximum sensitivity and specificity of the test. Full article
(This article belongs to the Special Issue Spintronic and Magnetic Platforms for Biosensing)
Show Figures

Figure 1

Back to TopTop