From Low-Tier to Individual Effects of Emerging Pollutants: Integrative Approaches to Ecotoxicological Assessments—2nd Edition
A special issue of Toxics (ISSN 2305-6304). This special issue belongs to the section "Ecotoxicology".
Deadline for manuscript submissions: 28 March 2025 | Viewed by 83
Special Issue Editors
Interests: environmental toxicology; exposure assessments; omics technologies (tran-scriptomics, proteomics, lipidomics); biomarkers; mechanisms of toxicity; adverse outcome pathways
Special Issues, Collections and Topics in MDPI journals
Interests: omics technologies; biomarkers; biotechnology
Special Issues, Collections and Topics in MDPI journals
Interests: ecotoxicogenomics; adverse outcome pathways; soil and aquatic biodiver-sity; ecosystems
Special Issues, Collections and Topics in MDPI journals
Special Issue Information
Dear Colleagues,
The prevailing paradigm of toxicological assessments, which predominantly emphasize apical endpoints such as survival, is increasingly recognized as inadequate and in need of modernization. The initial responses to anthropogenic stressors are often manifested at the sub-cellular level, where they can precipitate significant impacts on an organism's fitness and broader ecosystem health. By employing an integrated approach that spans across various biological scales, the incorporation of sub-cellular endpoints can enhance the realism and significance of pollutant impact assessments. Such assessments may yield highly specific and integrative biomarkers, serving as rapid and sensitive indicators for the early detection of chemical effects and the elucidation of their toxicological mechanisms. These biomarkers can also be instrumental in the formulation of adverse outcome pathways (AOPs).
This Special Issue is dedicated to the exploration of comprehensive ecotoxicological evaluations, with an emphasis on the effects of emerging pollutants on non-target organisms. We invite submissions encompassing original research, case studies, and comprehensive reviews that integrate individual-level endpoints—such as survival, growth, and behavior—with biochemical (e.g., oxidative stress and cellular damage) and molecular (e.g., gene expression and protein levels) assessments.
We look forward to receiving your contributions to the second edition of this important discourse.
Dr. Tiago Simoes
Dr. Hugo Monteiro
Dr. Nuno Ferreira
Guest Editors
Manuscript Submission Information
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Keywords
- biomarkers
- ecotoxicology
- emerging pollutants
- biological effects
- mode of action
- integrative analysis
- analytical methods
- sub-lethal endpoints
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