Advances in Cyanotoxins: Latest Developments in Risk Assessment

A special issue of Toxins (ISSN 2072-6651). This special issue belongs to the section "Marine and Freshwater Toxins".

Deadline for manuscript submissions: 30 November 2024 | Viewed by 898

Special Issue Editors


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Guest Editor
Department of Food Science, Toxicology and Legal Medicine, Faculty of Pharmacy, University of Sevilla, 41012 Sevilla, Spain
Interests: toxicology; risk assessment; food safety; cyanotoxins; microcystins; cylindrospermopsin
Special Issues, Collections and Topics in MDPI journals

E-Mail Website
Guest Editor
Department of Food Science, Toxicology and Legal Medicine, Faculty of Pharmacy, University of Sevilla, 41012 Sevilla, Spain
Interests: toxicology; risk assessment; food safety; cyanotoxins; microcystins; cylindrospermopsin
Special Issues, Collections and Topics in MDPI journals

Special Issue Information

Dear Colleagues,

Harmful algae blooms and cyanotoxin production have expanded their occurrence, driven by climate change. On the other hand, the establishment of legal limits follows a slower pace, hampered by the limitations in the toxicological databases. Microcystins and cylindrospermopsins are two of the more extensively investigated cyanotoxins, although their toxicological profiles have not yet been fully elucidated. For other different cyanotoxins, much more research is required to gain insight into their potential risks.

This Special Issue of Toxins focuses on recent developments in the risk assessment of cyanotoxins in a broad sense including hazard identification and assessment, exposure evaluation and risk characterization in relation to their impact on human and environmental health.

In this Special Issue, original research articles and reviews are welcome. Research areas may include (but not limited to) the following:

  • Toxicokinetics: uptake, distribution, metabolism and elimination;
  • Study of toxicity mechanisms and identification of adverse outcome pathways;
  • Toxicological evaluation using in silico, in vitro and in vivo methods;
  • Determination of the content and potential accumulation of cyanotoxins in water and food chain, including novel analytical approaches;
  • Identification and toxicity of degradation products;
  • Updated occurrence data and worldwide distribution;
  • Risk characterization;
  • Effects of multiple exposure to cyanotoxins and other environmental contaminants;
  • Potential strategies to prevent or ameliorate cyanotoxins’ toxicity.

Prof. Dr. Ana M. Cameán
Prof. Dr. Ángeles Jos
Guest Editors

Manuscript Submission Information

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Keywords

  • cyanotoxins
  • toxicokinetics
  • toxicity
  • exposure
  • risksWe look forward to receiving your contributions.

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Published Papers (1 paper)

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Research

22 pages, 6584 KiB  
Article
Persistence of Microcystin in Three Agricultural Ponds in Georgia, USA
by Jaclyn E. Smith, James A. Widmer, Jennifer L. Wolny, Laurel L. Dunn, Matthew D. Stocker, Robert L. Hill, Oliva Pisani, Alisa W. Coffin and Yakov Pachepsky
Toxins 2024, 16(11), 482; https://doi.org/10.3390/toxins16110482 - 7 Nov 2024
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Abstract
Cyanobacteria and their toxins can have multiple effects on agricultural productivity and water bodies. Cyanotoxins can be transported to nearby crops and fields during irrigation and may pose a risk to animal health through water sources. Spatial and temporal variations in cyanotoxin concentrations [...] Read more.
Cyanobacteria and their toxins can have multiple effects on agricultural productivity and water bodies. Cyanotoxins can be transported to nearby crops and fields during irrigation and may pose a risk to animal health through water sources. Spatial and temporal variations in cyanotoxin concentrations have been reported for large freshwater sources such as lakes and reservoirs, but there are fewer studies on smaller agricultural surface water bodies. To determine whether spatiotemporal patterns of the cyanotoxin microcystin occurred in agricultural waters used for crop irrigation and livestock watering, three agricultural ponds on working farms in Georgia, USA, were sampled monthly within a fixed spatial grid over a 17-month period. Microcystin concentrations, which ranged between 0.04 and 743.75 ppb, were determined using microcystin–ADDA ELISA kits. Temporal stability was assessed using mean relative differences between microcystin concentrations at each location and averaged concentrations across ponds on each sampling date. There were locations or zones in all three ponds that were consistently higher or lower than the average daily microcystin concentrations throughout the year, with the highest microcystin concentrations occurring in winter. Additionally, microcystin patterns were strongly correlated with the patterns of chlorophyll, phycocyanin, and turbidity. The results of this work showed that consistent spatiotemporal patterns in cyanotoxins can occur in produce irrigation and livestock watering ponds, and this should be accounted for when developing agricultural water monitoring programs. Full article
(This article belongs to the Special Issue Advances in Cyanotoxins: Latest Developments in Risk Assessment)
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