Molecular Surveillance and New Diagnostic Tests for Leishmaniasis
A special issue of Tropical Medicine and Infectious Disease (ISSN 2414-6366). This special issue belongs to the section "Vector-Borne Diseases".
Deadline for manuscript submissions: 15 February 2025 | Viewed by 1317
Special Issue Editors
Interests: molecular diagnosis; leishmaniasis; isothermal DNA amplification; molecular surveillance
Interests: molecular diagnosis; leishmaniasis; isothermal DNA amplification; molecular surveillance
Special Issue Information
Dear Colleagues,
Leishmaniasis is an important disease complex caused by protozoan parasites of the genus Leishmania, considered a neglected tropical disease (NTD). It is usually classified according to clinical presentation as tegumentary (TL) or visceral (VL) leishmaniasis. Significant efforts have been made in the past few decades to control and/or eliminate NTDs, leishmaniasis included. The World Health Organization’s (WHO) defined road map (2021–2030) for control and/or elimination of NTDs and specific goals for leishmaniasis recognizes that diagnostics plays a central role in the achievement of such goals.
The laboratory tests currently available for the diagnosis of TL and VL do not provide sufficient accuracy to be considered the gold standard. Among diagnostic tests, PCR techniques have been applied for leishmaniasis diagnosis with remarkable accuracy. However, generally, molecular tools require advanced laboratory facilities, making them difficult to implement in remote areas from high leishmaniasis-burden countries. The development or improvement of molecular tests is essential not only for the diagnosis of leishmaniasis but also for the implementation of molecular surveillance. There are still few initiatives for molecular surveillance of leishmaniasis. The implementation of molecular surveillance will allow monitoring the evolution of epidemics in time and space, characterizing new transmission cycles, and detecting new Leishmania variants related to new clinical features that are fundamental to the control of leishmaniasis.
This Special Issue aims to publish original articles, reviews and mini-reviews, case reports, and short communications that are related to the development or improvement of molecular tests for the diagnosis of human and animal leishmaniasis and molecular surveillance of leishmaniasis.
Dr. Daniel Moreira De Avelar
Dr. Andreza Pain Marcelino
Dr. Liliane De Fátima Antonio
Guest Editors
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Keywords
- molecular diagnosis
- visceral leishmaniasis
- tegumentary leishmaniasis
- genomic surveillance
- human leishmaniasis
- animal leishmaniasis
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