Tropical Protozoan Diseases: Discovery and Development of Antiparasitic Drugs
A special issue of Tropical Medicine and Infectious Disease (ISSN 2414-6366).
Deadline for manuscript submissions: closed (5 February 2024) | Viewed by 3247
Special Issue Editor
Special Issue Information
Dear Colleagues,
Tropical diseases caused by protozoa affect more than one billion people worldwide, with 90% of those infected living in developing countries. With limited resources, research and infrastructure investment to control these diseases has been insufficient. With devastating social and economic consequences, diseases such as malaria, leishmaniasis, Chagas disease, human African trypanosomiasis, and toxoplasmosis are responsible for great morbidity and mortality worldwide. Clinical manifestations reveal distinct epidemiological profiles which depend on the species, the region involved, and the patient's immunological conditions. For most tropical diseases, the current treatments are outdated and present significant drawbacks, including toxicity, the need for hospitalization, drug resistance, and high costs. New treatments for tropical diseases are urgently needed.
This Special Issue on Tropical Medicine and Infectious Diseases aims to gather relevant manuscripts involving basic, translational, and clinical research, and covering various advances in treatment for tropical diseases caused by protozoa. For this research topic, we are inviting interested researchers to share their original research, relevant findings, and review articles in the areas of:
- anti-protozoan drug identification;
- drug combinations;
- immunotherapy;
- drug-delivery systems;
- parasite drug resistance;
- target identification—validation for tropical protozoan diseases of medical interest.
Prof. Dr. Klinger Antonio da Franca Rodrigues
Guest Editor
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Keywords
- neglected diseases
- drug development
- leishmaniasis
- trypanosomiasis
- toxoplasmosis
- malaria
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