Detection of SARS-CoV-2 Neutralizing Antibodies and Vaccine Development: 2nd Edition
A special issue of Vaccines (ISSN 2076-393X). This special issue belongs to the section "COVID-19 Vaccines and Vaccination".
Deadline for manuscript submissions: 31 March 2025 | Viewed by 164
Special Issue Editor
Interests: SARS-CoV-2; HIV-1; HPV; vaccine development; vaccine evaluation; immune response; neutralizing antibody; standardization of assay
Special Issues, Collections and Topics in MDPI journals
Special Issue Information
Dear Colleagues,
The COVID-19 pandemic has been ongoing for more than four years, claiming the lives of over 7 million people and significantly impacting the lives of many. Vaccines are seen as a crucial tool in ending the outbreak, and it is important to have safe, effective, affordable, and accessible vaccines. Neutralizing antibodies play a key role in evaluating the effectiveness of SARS-CoV-2 vaccines. There is an urgent need for standardized in vitro potency methods to assess antiviral products in both pre-clinical and clinical phases. Detecting neutralizing antibodies against SARS-CoV-2 can help understand the protective immune response in COVID-19 patients and asymptomatic cases. Currently, there are various methods for detecting SARS-CoV-2 neutralizing antibodies, but differences in laboratory procedures can lead to incomparable results. This makes it difficult to compare the immunogenicity of different vaccines. To gain a better understanding of recent scientific knowledge and current trends in SARS-CoV-2 neutralization assay and vaccine development, this Special Issue focuses on recent scientific and technical progress in this field. This Special Issue welcomes original research articles and reviews covering recent advances in novel neutralization assay development, standardization and comparison of different SARS-CoV-2 neutralization assays, comparison of neutralizing antibody responses induced by different vaccines, and correlates of protection.
I look forward to receiving your contributions.
Dr. Jianhui Nie
Guest Editor
Manuscript Submission Information
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Keywords
- COVID-19
- SARS-CoV-2
- vaccine
- neutralizing antibody
- correlation of protection
- standardization
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