Impact of Vaccines and Vaccination on the Gut Microbiota

A special issue of Vaccines (ISSN 2076-393X).

Deadline for manuscript submissions: 30 June 2025 | Viewed by 829

Special Issue Editor

Center for Vaccine Development and Global Health, Department of Medicine, University of Maryland School of Medicine, Baltimore, MD 21201, USA
Interests: gram-negative bacteria; vaccines; glycobiology; immune response; biodefense
Special Issues, Collections and Topics in MDPI journals

Special Issue Information

Dear Colleagues,

The gut microbiome has an important role in human health. One area where the gut microbiome has a significant impact is in vaccination. Antibiotics or probiotics have been shown to alter the gut microbiome and may affect immunization responses. Still, it remains unclear whether vaccines can alter the gut microbiome and if the mode of vaccine delivery affects the GI microbiome. Vaccines may be able to target specific pathogens, such as multidrug-resistant (MDR) pathogens, without affecting the rest of the gut microbiome, and the impact of the gut microbiome on cancer and veterinary vaccines is an emerging research area. Submissions on these and other issues are welcomed to this Special Issue, titled “Impact of Vaccines and Vaccination on the Gut Microbiota”.

Dr. Alan Cross
Guest Editor

Manuscript Submission Information

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Keywords

  • vaccine
  • vaccination
  • gut microbiota
  • immune response
  • colonization

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Published Papers (1 paper)

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10 pages, 417 KiB  
Conference Report
NIAID Workshop Report: Systematic Approaches for ESKAPE Bacteria Antigen Discovery
by Inka Sastalla, Keehwan Kwon, Clayton Huntley, Kimberly Taylor, Liliana Brown, Tamika Samuel and Lanling Zou
Vaccines 2025, 13(1), 87; https://doi.org/10.3390/vaccines13010087 - 18 Jan 2025
Viewed by 413
Abstract
On 14–15 November 2023, the National Institute of Allergy and Infectious Diseases (NIAID) organized a workshop entitled “Systematic Approaches for ESKAPE Bacteria Antigen Discovery”. The goal of the workshop was to engage scientists from diverse relevant backgrounds to explore novel technologies that can [...] Read more.
On 14–15 November 2023, the National Institute of Allergy and Infectious Diseases (NIAID) organized a workshop entitled “Systematic Approaches for ESKAPE Bacteria Antigen Discovery”. The goal of the workshop was to engage scientists from diverse relevant backgrounds to explore novel technologies that can be harnessed to identify and address current roadblocks impeding advances in antigen and vaccine discoveries for the ESKAPE pathogens (Enterococcus faecium, Staphylococcus aureus, Klebsiella pneumoniae, Acinetobacter baumannii, Pseudomonas aeruginosa, and Enterobacter species). The workshop consisted of four sessions that addressed ESKAPE infections, antigen discovery and vaccine efforts, and new technologies including systems immunology and vaccinology approaches. Each session was followed by a panel discussion. In total, there were over 260 in-person and virtual attendees, with high levels of engagement. This report provides a summary of the event and highlights challenges and opportunities in the field of ESKAPE vaccine discovery. Full article
(This article belongs to the Special Issue Impact of Vaccines and Vaccination on the Gut Microbiota)
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