Vaccines against Poultry Viruses

A special issue of Vaccines (ISSN 2076-393X). This special issue belongs to the section "Veterinary Vaccines".

Deadline for manuscript submissions: 31 December 2025 | Viewed by 443

Special Issue Editor

Key Laboratory of Animal Microbiology of China’s Ministry of Agriculture, College of Veterinary Medicine, Nanjing Agricultural University, Nanjing 210095, China
Interests: poultry vaccines; immune enhancers; respiratory diseases; development of humoral and cellular immune vaccines; mucosal immune vaccine
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Special Issue Information

Dear Colleagues,

Poultry viral infectious diseases have caused heavy economic losses in the poultry industry, which has also caused serious threats to human health—especially concerning zoonotic infectious diseases. In the modern breeding industry, poultry are highly concentrated and frequently transported, which makes them more vulnerable to infectious diseases.

Therefore, veterinary vaccine research in poultry and related animal infectious diseases is increasingly important. Poultry viral infectious diseases have a broadly intersecting and close relationship with other disciplines in veterinary science. The spread and expansion mechanism of avian influenza virus has attracted widespread attention from researchers, which promotes the development of universal vaccines against the influenza virus infection. The differences and vaccine development between avian coronavirus, human coronavirus, and other animal species of coronaviruses are also important research topics. Also, the clinical variation patterns of the Newcastle disease virus and vaccine development are highly noteworthy priorities. Some avian immunosuppressive viral diseases and avian tumor diseases pose serious threats to the healthy development of the poultry industry, and the diagnostic technology and vaccine development of these related diseases are crucial. In addition, the development of new avian virus-vectored vaccines and the current application status and improvement measures of conventional vaccines are also the focus of this Special Issue.

This Special Issue focuses on recent vaccine research in important clinical virus infectious diseases in poultry, waterfowl, pigeons, and wild birds, including immunosuppressive diseases, respiratory syndrome diseases, and gastrointestinal diseases. Furthermore, the related detection and basic knowledge of immunology and immune adjuvant and enhancers are of great concern. Additionally, the development of scientific and standardized diagnoses and monitoring techniques for newly emerging avian viral diseases is also of great interest to us.

The research subjects of interest for this Special Issue include poultry, waterfowl, pigeons, wild birds, etc.

In this Special Issue, original research articles and reviews are welcome. We encourage all scientists working in these fields to publish their experimental results and conceptual summaries in this Special Issue.

We look forward to receiving your contributions.

Dr. Xiuli Feng
Guest Editor

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Keywords

  • poultry and waterfowl
  • pigeons
  • wild birds
  • viral diseases
  • immunosuppressive disease
  • respiratory syndrome disease
  • poultry tumor diseases
  • immunoenhancers and adjuvants
  • genetically engineered vaccines
  • biosafety management of clinical veterinarians
  • antiviral drugs

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Published Papers (1 paper)

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Research

13 pages, 3223 KiB  
Article
Live Attenuated aTJ Vaccine Effectively Protects Pigeons Against Homologous PPMV-1 Challenge
by Shan Zhang, Dahu Liu, Baojing Liu, Ruinying Liang, Lin Liang, Xinming Tang, Shaohua Hou, Chan Ding, Xusheng Qiu and Jiabo Ding
Vaccines 2024, 12(12), 1304; https://doi.org/10.3390/vaccines12121304 - 22 Nov 2024
Viewed by 113
Abstract
Background: Pigeon paramyxovirus type 1 (PPMV-1) is a significant pathogen affecting pigeon populations globally. The commonly used La Sota vaccine provides limited protection due to antigenic divergence from circulating PPMV-1 strains. An antigenically matched vaccine is needed to address this challenge. Methods: An [...] Read more.
Background: Pigeon paramyxovirus type 1 (PPMV-1) is a significant pathogen affecting pigeon populations globally. The commonly used La Sota vaccine provides limited protection due to antigenic divergence from circulating PPMV-1 strains. An antigenically matched vaccine is needed to address this challenge. Methods: An attenuated aTJ strain was developed through reverse genetics by modifying the F protein cleavage site of the virulent TJ-WT strain. Pigeons were immunized twice with the aTJ strain via eyedrop and intranasal routes, followed by a challenge with a virulent PPMV-1 strain ten days after the booster immunization. Results: The attenuated aTJ strain induced robust serum antibody titers post-booster immunization, and vaccinated pigeons showed strong protection upon challenge, with significantly reduced morbidity, mortality, and viral shedding compared to controls. Conclusions: These findings suggest that the aTJ strain is a promising candidate for the promotion of PPMV-1 prevention and control, emphasizing the importance of antigenic matching in optimizing vaccine efficacy. Full article
(This article belongs to the Special Issue Vaccines against Poultry Viruses)
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