Muscle Tone Physiology and Abnormalities
Round 1
Reviewer 1 Report
In this review, authors well focalize normal homeostatic mechanisms maintaning tone and its pathophysiology. All paragraphs are well organized and comprehensively described; review is scientifically sound and not misleading with appropriate and adequate references related and previous work. Moderate English changes required. So, I conclude work could be accept after minor English revision
Author Response
We thank the reviewer for the comment. We have edited some lines.
Reviewer 2 Report
Suggestions:
Line 27: Spasticity and rigidity, the two types/forms of hypertonia
Line 80: The anatomy underlying the regulation of muscle tone
Lines 393-4- Dystonia is not infrequently found in spinocerebellar ataxias, but rarely is it a presenting symptom
Lines 395-6- SCA6 manifests as a pure cerebellar ataxia /as a pure ataxia phenotype; When present, dystonia cannot be explained (...)
Author Response
We thank the reviewer for the comments. He have edited the lines and have highlighted the changes.
1. Line 27: Spasticity and rigidity, the two types/forms of hypertonia
Ans: We have edited the line.
2. Line 80: The anatomy underlying the regulation of muscle tone
Ans: We have edited the line.
3. Lines 393-4- Dystonia is not infrequently found in spinocerebellar ataxias, but rarely is it a presenting symptom
Ans: We have edited the line.
4. Lines 395-6- SCA6 manifests as a pure cerebellar ataxia /as a pure ataxia phenotype; When present, dystonia cannot be explained (...)
Ans: We have edited the line.
