1. Introduction
Capsule endoscopy has emerged as a prominent non-invasive diagnostic method for assessing the health of the gastrointestinal (GI) tract. It utilizes a miniaturized capsule-shaped device equipped with a camera system to capture images of the GI tract. The captured images are subsequently transmitted to external recording devices for further analysis by a physician [
1]. However, the observation is limited to superficial information on the GI tract. The remarkable ability of endoscopic ultrasound (EUS) to image deep tissues has sparked considerable interest in its integration with capsules, aiming to augment diagnostic depth. Traditional EUS systems feature a single-element ultrasonic transducer at the catheter’s tip. Single-element transducers, while simpler in construction compared to array transducers, are constrained by a fixed focal point. As a result, they are capable of targeting only one area at a time, which requires frequent mechanical realignment to achieve comprehensive 360-degree scanning and subsequently construct two-dimensional images. It also means that conventional single-element EUS systems should incorporate an electromagnetic motor that drives a flexible shaft, allowing the transducer to mechanically rotate and acquire a complete 360-degree perspective. However, electromagnetic motors, typically large and complex, are often situated far from the transducer, thereby limiting the rotational velocity of EUS systems. Then, the imaging frame rate is also constrained by the time-consuming nature of mechanical scanning techniques [
2,
3,
4]. Furthermore, integrating the single-element imaging system directly into the capsule is challenged by the limited space available within it.
To solve these problems, radial array ultrasound transducers have attracted increasing attention. The foundational principle of achieving focus with radial array transducers relies on the application of exact time delays to the excitation signals of each constituent element within the array. This method facilitates the coherent summation of acoustic waves at a designated focal point, culminating in the formation of an intensified acoustic field. This also suggests that radial array transducers are capable of enabling 360-degree electronic scanning, eliminating the necessity for supplementary mechanical components [
3,
4,
5,
6,
7]. Hence, radial array transducers hold enormous potential for quicker image acquisition and enhanced clarity in capsule endoscopy. Nevertheless, the successful implementation of these transducers still faces several challenges that need to be addressed urgently. Firstly, to achieve the necessary resolution and image quality, a sufficient number of piezoelectric elements must be accommodated within the confined space of the capsule, necessitating a reduction in the size of individual transducer elements to specific dimensions. Secondly, piezoelectric ceramics, which serve as the core excitation components for ultrasound transducers owing to their superior electromechanical properties, are inherently brittle. This brittleness poses a significant risk of element fracture during the rolling process needed to form the cylindrical array. Consequently, the complexity of fabricating radial array transducers hinders their broader application.
Although piezopolymers like polyvinylidene fluoride (PVDF) exhibit favorable acoustic impedance matching with human tissues and remarkable flexibility, their utilization as the active material in radial array transducers is constrained by their inherently low piezoelectric coefficients [
2]. To enhance the performance of piezoelectric materials for their suitability in radial array transducers, composites are developed. Among them, 1-3 composite, consisting of piezoelectric rods and filled passive epoxy resin, are a more suitable option for the active material of radial ultrasonic transducers because of their superior electromechanical coupling coefficient and enhanced flexibility. Additionally, the acoustic impedance of composites closely matches that of human tissues, facilitating efficient energy transfer and minimizing impedance mismatch-induced losses. Over the past few decades, intensive research efforts have been devoted to the development of radial array transducers employing 1-3 composite materials. Zhou et al. reported a radial array transducer that uses PMN-PT single crystal/epoxy 1-3 composite and is fabricated by the wrapping method [
2]. Zhang et al. fabricated a 6.8-MHz 128-element endoscopic ultrasonic transducer based on high-performance PMN-PT 1-3 composite [
6]. Subsequently, Zhang et al. explored and constructed an 84 × 5 element 1.5-dimensional circular array transducer [
8]. Nevertheless, the element pitch in these transducers exceeds a wavelength in the medium, which is relatively large and may lead to the formation of grating lobes at the operation frequency. Then, the performance of the imaging system is degraded by introducing errors and artifacts in the final image. Moreover, the crosstalk phenomenon between adjacent elements existing in the above-developed radial array transducers has not been thoroughly investigated.
This study is dedicated to developing a miniaturized radial array transducer made of 1-3 piezoelectric composite for integration into an endoscopic capsule. In light of the dimension features of existing endoscopy capsules, a 2.5 MHz, 64-element radial ultrasonic transducer was developed using a bending-and-superposition method. This transducer, crafted from high-performance PZT-5H/epoxy 1-3 composites, has a diameter of approximately 12.8 mm and a length of 11 mm. The method is simple to implement and suitable for the processing of radial transducers of any size. In addition, its performance, especially crosstalk, is simulated. According to the simulation results, array elements are precisely spaced at a pitch of 600 μm, which corresponds to one wavelength in water and is suitable for improving imaging capabilities. Given the requirements of narrow pitch and kerf width between adjacent elements, electrical connections were accomplished by a pre-designed flexible circuit with rectangular pads. The flexible circuit board is simple in design, cheap, and can realize precise excitation of piezoelectric elements. Lastly, the electrical and acoustic performance of the fabricated transducer, including impedance characteristics, pulse-echo response, and crosstalk, was characterized by adopting conventional test methods. The transducer mainly vibrates in thickness (k33) mode and exhibits a higher electromechanical coupling factor. Meanwhile, due to the larger kerf width, the crosstalk between array elements is also significantly reduced. These test outcomes demonstrate that the fabricated radial array transducer exhibits outstanding performance.
2. Materials and Fabrication Methods
For 1-3 composite consisting of ceramic and epoxy, piezoelectric ceramic square columns are actual sound-emitting and receiving components. Ideally, these columns should vibrate in the
k33 mode. Then, the ceramic and epoxy 1-3 composite can achieve a larger electromechanical coupling factor
kt. In this article, PZT-5H/epoxy 1-3 composite was chosen as the active material due to its superior electromechanical coupling coefficient. This characteristic signifies an excellent conversion efficiency between electrical and acoustic energies in a longitudinal resonance mode [
9]. Moreover, the acoustic impedance of this composite is much closer to that of human tissues, making it ideal for broad bandwidth and high-sensitivity ultrasonic transducers. The composite utilized in our research was supplied by Zhongshan City Shengnuo Instrument Equipment Co., LTD (Zhongshan, China). The key property parameters of PZT-5H/epoxy 1-3 composite can be found in
Table 1.
The characteristics of the PZT-5H composite-based material were instrumental in refining the design parameters for our circular array transducer. This optimization process encompasses the thicknesses of the piezoelectric layer, the backing layer, and the dimensions of each element [
6], as referenced in
Table 2. The simulation software employed for this task included PiezoCAD (version 4.01.), which is based on the Krimboltz, Leedom, and Mattaei (KLM) model (developed by Sonic Concepts, Woodinville, WA, USA), and the finite element analysis software Comsol6.2. Given the small acoustic impedance discrepancy between the PZT-5H/epoxy 1-3 composite and water, the matching layer is neglected. The final design parameters for the transducer are detailed in
Table 2. The pitch of the radial array transducer was designed to be λ for the suppression of grating lobes during beam steering. Furthermore, to reduce crosstalk between adjacent elements, the kerf size was intentionally made larger.
Figure 1 shows the fabrication procedure of the radial array transducer. Firstly, the 1-3 piezocomposite was fabricated based on a PZT-5H plate. In order to reduce the coupling effect of the transverse vibration mode, the ratio of height to width for the embedded ceramic rods should generally be as large as possible [
10]. Considering the fragility of piezoelectric ceramics, the composite with the desired aspect ratio was prepared by the dice-and-fill method. The specific preparation process is also illustrated in
Figure 1a. Specifically, the widths of piezoelectric columns and filled epoxy are, respectively, 120 μm and 80 μm. According to the central frequency parameter, the piezoelectric composite sample was prepared at the desired thickness of about 620 μm. The thickness of the radial array transducer has been approximately optimized to half the wavelength (λ/2), with λ representing the wavelength at the resonant frequency.
Both the top and bottom sides of the piezoelectric composite sample were then mechanically polished and sputtered with a Cr/Au (50/100 nm) electrode. The dimensions of the manufactured composite are 45 × 45 mm2. Subsequently, the composite was cut into multiple separate sections (1/4 planar unit) with a length of 9.6 mm and a width of 11 mm. After that, four 1/4 planar units were picked. The negative electrode of the 1/4 planar unit was cut into 16 elements. Then, the dispersed four 1/4 planar units were adhered to flexible circuit boards using insulating epoxy (EPO-TEK 301, Epoxy Technology, Billerica, MA, USA). Flexible circuits (10 × 15 mm2) were used to simplify the electrical connection to the separated elements. The length of the flexible circuit board, 10 mm, is approximately equal to that of a 1/4 planar unit in order to allow it to be inserted inside the capsules.
However, its width, 15 mm, is larger than that of a 1/4 planar unit in order to ensure a successful electric connection between all transducer elements and excitation signals. The width of each rectangular pad is 270 μm, which constitutes 68% of the width of the piezoelectric elements. In order to ensure optimal contact between the piezoelectric elements and pads, the length of the pads was set to 1 mm. Furthermore, all rectangular pads in flexible circuits should be aligned with the elements. An external stress was imposed on the 1-3 composite by a custom-made fixture in order to ensure thin bonding layers (3–5 μm). Concretely, each 1/4 planar unit attached with a flexible circuit board was clamped on two stainless cuboids assisted with fastening thread at 40 °C for 2 h. After 24 h, screw fastening nuts with a diameter of 3 mm were placed into the through-hole of the 1st fixture and tightened slightly at 80 °C. Then, the dispersed four parts can be bent to a 90-degree angle by exploiting the 1st fixture.
To shorten the ring downtime and reduce the reverberation of ultrasonic transducers, a backing layer was added. It should be noted that using the backing layer can increase the bandwidth of the transducer while sacrificing a part of the acoustic energy. Therefore, a moderate value of acoustic impedance for the backing layer (5.8 MRrayls) was selected to balance the bandwidth and sensitivity of the radial array transducer.
Using the EPO-TEK 301 and the 2nd fixture, four 90-degree curved modules were pasted onto the prepared backing layer and assembled into radial array transducers with 64 elements. Meanwhile, nuts with a diameter of 5 mm were also utilized to apply radial pressure in order to ensure that four 90-degree curved modules could be successfully attached to the backing layer. Additionally, there are four 90-degree alignment lines on the top surface of the 2nd fixture to guarantee the precise conjunction of four independent units. In order to easily observe the position of four 90-degree curved components during the experiment and adjust them accurately, the 2nd fixture was set to be transparent.
Figure 1b illustrates the decomposition view of fabricating a 64-element circular transducer using the 2nd fixture. A metal pillar was placed inside the backing layer to support the transducer.
Figure 1c shows the 90-degree transducer after bending. As shown in
Figure 1c, gaps exist in the 90-degree warped transducer. EPO-TEK 301 was used to fill in the spaces between different elements. The inner electrode of the radial array transducer was connected to electric excitation signals. The outer electrode was regarded as ground. In order to ensure that the outer electrodes of the 64 elements are interconnected, E-solder 3022 was applied. Finally, a 10 μm thick parylene (Parylene C, Specialty Coating Systems, Indianapolis, IN, USA) layer was vapor-deposited onto the external surface of the transducer by a parylene coater (Diener P6, Polyp-xylene coating system, Diener electronic, Ebhausen, Germany). The parylene acts as a matching layer between the designed radial array transducer and operating medium in order to coordinate their acoustic impedances. This parylene layer can also be used to protect wire bonds.
The fabricated radial array transducer, depicted in
Figure 1d, features lead-out wires comprising 64 signal wires and 2 ground wires. Each array element, with a width of 400 μm, is composed of two rows of piezoelectric pillars and two rows of passive epoxy pillars. To minimize electric interference between adjacent elements, the kerf is designed to include one row of piezoelectric pillars and one row of passive epoxy pillars, with a width of 200 μm. Consequently, the center-to-center distance between two consecutive array elements is set at 600 μm, taking into account the fabrication challenges associated with electrical connections to small array elements and the stringent requirements of electrical systems. The spacing of electrical pads on the flexible circuit board is also maintained at 600 μm [
6].
3. Characterization
This section describes how to calculate and measure key performance parameters of ultrasonic transducers. Firstly, the effective electromechanical coupling coefficient, denoted as
keff, plays a pivotal role in characterizing the conversion efficiency between electrical and mechanical energies in ultrasonic transducers. The calculation of
keff is as follows:
where
fr and
fa, respectively, stand for the resonance and anti-resonance frequencies of the transducer. The higher value of
keff typically represents a larger efficiency of electroacoustic energy transfer and broader bandwidth. The resonance and anti-resonance frequencies are determined from the impedance and phase spectra of the radial array transducer, which are measured using an impedance analyzer (E4990A from Keysight Technologies Inc., Santa Rosa, CA, USA). In addition, the initial peak of element oscillations is identified as the resonance frequency, where the impedance reaches the minimum. With the frequency further increasing, the impedance increases to the maximum, which corresponds to the anti-resonance frequency.
The longitudinal resolution in ultrasonic imaging, which is the capacity to discern objects that are in close proximity along the path of the ultrasound beam, can be deduced from the characteristics of the echo signal in both the time domain and frequency spectrum. The transducer’s pulse-echo response was evaluated in a deionized water bath at ambient temperature, as referenced in [
11]. Barrel-shaped quartz blocks with varying internal diameters were crafted to facilitate the selection of a suitable reflector body for the designed ultrasonic transducer. The transducer was placed in the center of the chosen quartz reflector with a distance at the near field/far field transition point. By connecting to an ultrasound transducer analyzer (ProCheck SC5, Broadsound Corporation, Shenzhen, China), the active element was excited individually by a 1 J electrical impulse with a 500 Hz repetition rate and 50 Ω output impedance. The actuation voltage amplitude was set at −75 V. The frequency bandwidth, ranging from DC to 55 MHz, defines the spectrum of the ultrasound beam emitted by the transducer. The echo response was captured by the receiving module of the ultrasound transducer analyzer. The frequency domain pulse-echo response can also be acquired. The bandwidth of the transducer was ascertained from the −6 dB points on the frequency spectrum. We denote the lower and upper −6 dB frequencies as
f1 and
f2, respectively, which correspond to the frequencies where the displacement amplitude is 50% (6 dB) of its peak value. Then, the center frequency is given by
The −6 dB bandwidth can be described as
The mechanical quality factor,
Qm, significantly impacts both the waveform emitted by the transducer and the response curve observed during signal reception. Typically,
Qm can be calculated as
The two-way insertion loss (
IL), also known as the relative pulse-echo sensitivity, is the ratio of transducer output power
Po to input power
Pi delivered to the transducer from a driving source. If the output resistance
Ro is assumed to be equal to the input resistance
Ri, the
IL can be simplified as the ratio of the echo voltage
Vo to the excitation voltage
Vi [
2].
The radial array transducer was actuated by a function generator (RIGOL DG4162), which produced a 20-cycle sinusoidal pulse with a peak amplitude of
V1 at the central frequency
fc. In response to this excitation signal, the transducer would receive an echo signal with an amplitude of
Vo, as detected by an oscilloscope (SDS5104X) with an input impedance of 1 MΩ. For reference, the amplitude of the driving signal
Vi was measured under a 50 Ω impedance condition, as noted in [
12].
Crosstalk arises from the vibrational coupling effect between an activated transducer element and its neighboring elements. When a voltage signal is applied to stimulate a transducer element, ultrasonic vibrations are generated through the
d33 piezoelectric effect. These mechanical vibrations can travel to adjacent elements, leading to unintended interactions. After receiving a pulse signal reflected by an interface, an electric signal can be generated by exploiting the inverse piezoelectric effect. Crosstalk can also distort the directivity characteristic of aperture in array transducers, which in turn degrades the quality of ultrasound images, as indicated in [
13]. The degree of electrical and acoustical separation between elements is quantified by measuring the crosstalk level. To evaluate the interference between adjacent elements, a simulation is conducted in the time domain where a single element is activated, and the electric voltage of neighboring, non-intentionally stimulated elements is calculated. This process helps determine the extent to which adjacent elements contribute to mechanical crosstalk in ultrasonic transducers. In finite element simulation analysis, three cycles of sinusoidal wave signal whose amplitude is
v0 are supplied to activate an element and then the voltage amplitude of adjacent elements (
va) can be calculated. Based on these calculations, the crosstalk level (CTL) is defined by the following equation [
14,
15]:
5. Conclusions
A 2.5 MHz PZT-5H/epoxy 1-3 composite radial array transducer with 64 elements was designed and fabricated by a bending-and-superposition method. Array elements were spaced at a 600 μm pitch, equivalent to one wavelength in water. This configuration is instrumental in mitigating grating lobes for the presented radial transducers. The kerf width is 200 μm, which is beneficial in reducing the crosstalk level between array elements. A flexible circuit board with rectangular pads was designed and manufactured to simplify the electrical connection between the array elements and the driving system. Key performance parameters, including the pulse-echo response, impedance, acoustic field distribution, crosstalk, vibration mode, central frequency, etc., were all simulated to evaluate the behaviors of the radial array transducer. The simulated results suggest that piezoelectric elements in 1-3 composite mainly tend to vibrate in the k33 mode, and a larger electromechanical coupling factor kt can be achieved. The outer diameter of the manufactured transducer is around 12.8 mm. The fabricated transducer manifests a low two-way insertion loss of 31.86 dB. The −6 dB bandwidth is 36%, which is reasonable for radial transducers. At the resonance frequency of 2.71 MHz, the electrical impedance of the measured element is around 1 kΩ. Meanwhile, the decrease in CTL for adjacent element 2 signifies a marked reduction in interference from the activated element.