Reproductive Endocrinology Assays: From Hormone Detection to a Clinically Relevant Decision
A special issue of Animals (ISSN 2076-2615).
Deadline for manuscript submissions: closed (29 February 2024) | Viewed by 339
Special Issue Editors
Interests: endocrinology; pregnancy; placenta; estrogens; androgens; progestogens; steroids; mare; cow; bison
Interests: endocrinology; pregnancy; placenta; PAG; Immuno-assays; cattle; buffalos; bisons
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Special Issue Information
Dear Colleagues,
Theriogenology practice often requires hormonal assays to confirm decisions, diagnosis or prognosis. Different steps are necessary to develop relevant methods: three equally critical concerns need to be addressed.
Find the target: The number of hormones and their metabolites suitable for assay is striking. The identification of potential markers or family of markers of interest requires knowledge of physiology and physio-pathology. On the other hand, serum is a commonly used and reliable matrix, but others could provide relevant results with adequate pre-analytic methods and could be easier to collect, such as saliva, feces, urine, milk or hairs.
Choose the weapon: Choosing an assay method depends on its price and the target’s nature, size and stability. In veterinary medicine, immuno-assays are cheap, easy to perform and widely used. However, mass spectrometry coupled to chromatography increases sensitivity, specificity and reproducibility for small molecules and enable multi-hormones assays.
Elude confusions: Hormone and precursor production is often mediated by different factors, either internal or external. Associated pathologies and physiological influences can lead to internal confusions, whereas environment and management will interfere as external confusion factors. Prospective evaluations of these influencing factors and their study is a key for success.
This Special Issue is dedicated to endocrine markers for fertility, pregnancy and reproductive pathologies.
Dr. Jérôme Ponthier
Dr. Olimpia Barbato
Guest Editors
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Keywords
- veterinary
- endocrinology
- hormone
- progestogens
- estrogens
- androgens
- gonadotropins
- LH
- FSH
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