In Vitro, In Vivo and Ex Vivo Veterinary Oncology Research and Treatment for Companion Animals

A special issue of Animals (ISSN 2076-2615). This special issue belongs to the section "Veterinary Clinical Studies".

Deadline for manuscript submissions: 10 September 2025 | Viewed by 63

Special Issue Editors


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Guest Editor
Department of Veterinary Sciences, University of Messina, Via G. Palatucci, 98168 Messina, Italy
Interests: veterinary pathology; mammary gland tumours; tumour microenvironment; translational medicine
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Guest Editor
Department of Chemical, Biological, Pharmaceutical and Environmental Sciences, University of Messina, Viale Ferdinando Stagno d’Alcontres 31, 98166 Messina, Italy
Interests: veterinary surgery; veterinary anaesthesia; translational medicine
Special Issues, Collections and Topics in MDPI journals

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Guest Editor
Department of Biotechnology Research and Diagnostics, Histopathology and Immunohistochemistry Laboratory, Istituto Zooprofilattico Sperimentale della Sicilia, 90129 Palermo, Italy
Interests: veterinary pathology; oncology; mammary tumours; histopathology; immunohistochemistry

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Guest Editor
Department of Veterinary Sciences, University of Messina, Via G. Palatucci, 98168 Messina, Italy
Interests: veterinary oncology; mammary tumours; translational medicine; tumour microenvironment

Special Issue Information

Dear Colleagues,

Veterinary oncology has made huge progresses in recent years, but there are still many areas that need attention. One of the greatest challenges in oncology is to identify an experimental model that can reproduce the complexity and dynamism of the tumour in order to find targeted treatments. In vitro cell cultures are the starting point for providing meaningful insights into specific research questions. However, these do not fully replicate the tumour microenvironment. In vivo models overcome this obstacle but are more time-consuming and often pose ethical concerns. Ex vivo cultures represent three-dimensional models that maintain the complexity of the tumour biology, often including the stromal microenvironment, and represent a promising method that needs to be exploited in further studies.

A deep knowledge of tumour biology makes it possible to identify new molecular and cellular targets and recognise the best pharmacological or surgical treatment.

This Special Issue aims to collect papers that further investigate veterinary oncology using in vitro, in vivo, or ex vivo research methods to improve the knowledge of tumours and their possible treatment in companion animals.

Dr. Alessandra Sfacteria
Dr. Cecilia Vullo
Dr. Roberto Puleio
Dr. Giada Giambrone
Guest Editors

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Animals is an international peer-reviewed open access semimonthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2400 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • in vitro, in vivo, ex vivo methods
  • veterinary oncology
  • tumour microenvironment
  • tumour cell cultures
  • companion animals
  • cancer treatment

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This special issue is now open for submission.
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