The Emergence of Multidrug Resistance: Genetic Mechanisms, Fitness Cost, and Dissemination in the Human-Environment Continuum
A special issue of Antibiotics (ISSN 2079-6382). This special issue belongs to the section "Mechanism and Evolution of Antibiotic Resistance".
Deadline for manuscript submissions: closed (30 June 2024) | Viewed by 2324
Special Issue Editors
2. Department of Public and Ecosystem Health, College of Veterinary Medicine, Cornell University, Ithaca, NY 14853, USA
Interests: medical microbiologist and molecular epidemiologist focused on infectious diseases and antimicrobial resistance, evidence-based medicine, and one Health interventions
Special Issues, Collections and Topics in MDPI journals
Interests: antimicrobial resistance; antibiotic resistance genes; bacterial fitness; bacterial adaptations; virulence; foodborne bacterial pathogens; infectious disease; One Health
Special Issues, Collections and Topics in MDPI journals
Special Issue Information
Dear Colleagues,
The misuse and over-reliance on antimicrobial drugs have driven the emergence and dissemination of multidrug-resistant (MDR) microorganisms. Although surveillance is an essential tool to assess the spread of MDR pathogens and the robustness of stewardship programs, there is a notable lack of data on antimicrobial use and AMR in many countries across the globe due to many factors, including high cost and specialized infrastructure. However, novel, rapid, and cost-effective methods have revolutionized AMR surveillance and epidemiology, allowing the use of whole genome and metagenomic sequencing at a broad scale across the globe. These technologies have the potential to greatly enhance AMR analysis and tracking at both the local and international levels. Gene/ genome sequencing is a useful epidemiological tool that allows the study of AMR gene transmission and links phenotypic susceptibility patterns to genetic determinants. To address the global challenge of AMR, genomic studies are critical to defining the factors and mechanisms that can mitigate the spread or resistance. These studies are valuable resources for guiding stakeholders, from policymakers to infection prevention specialists.
This Special Issue focuses on expanding genomic data on the global AMR threat and on filling knowledge gaps in our understanding of the transmission dynamics of AMR genes and mobile genetic elements. We cordially invite researchers working in these areas to contribute Original Research, Case Reports, and General and Systematic Reviews. Reports focused on low- and middle-income countries (LMICs) and disenfranchised populations/ settings are particularly welcomed.
Dr. Marwan Osman
Dr. Issmat Kassem
Guest Editors
Manuscript Submission Information
Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.
Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Antibiotics is an international peer-reviewed open access monthly journal published by MDPI.
Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2900 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.
Keywords
- antimicrobial resistance
- molecular epidemiology
- genome analysis
- gene sequencing
- next generation sequencing
- nucleotide polymorphism sequence
- mobile genetic elements
- plasmids
- resistance mechanisms
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